Evidence map›Paper›PMID 42098752›Full record

ArticleBMC public health2026

Body mass index modifies cardiovascular risk trajectory: a Chinese longitudinal cohort study.

Jingyu Wang, Yanyan Zhang, Mengyao Liu, Fangchao Liu, Keyong Huang, Shufeng Chen, Jie Cao, Yan Wang, Chong Shen, Xiaoqing Liu and 8 more

Abstract read
In one paragraph

Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jingyu WangDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Yanyan ZhangDepartment of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Mengyao LiuDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Fangchao LiuDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Keyong HuangDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Shufeng ChenDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Jie CaoDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Yan WangDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Chong ShenDepartment of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Xiaoqing LiuDivision of Epidemiology, Guangdong Provincial People's Hospital and Cardiovascular Institute, Guangzhou, China.
Ling YuDepartment of Cardiology, Fujian Provincial Hospital, Fuzhou, China.
Huan ZhangDepartment of Epidemiology, School of public health, Medical College of Soochow University, Suzhou, China.
Shujun GuDepartment of Chronic Disease Control and Prevention, Changshu Center for Disease Control and Prevention, Changshu, China.
Dongsheng HuDepartment of Biostatistics and Epidemiology, School of Public Health, Shenzhen University Health Science Center, Shenzhen, China.
Jianfeng HuangDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Dongfeng GuDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China.
Xiangfeng LuDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China. luxf@pumc.edu.cn.
Jianxin LiDepartment of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No.167 Beilishi Road, Xicheng District, Beijing, 100037, China. leeljx@126.com.

Funding

Capital's Funds for Health improvement and Research 2024-1G-4033Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences 2021-2M-1-010National High Level Hospital Clinical Research Funding 2025-GSP-GG-32National High Level Hospital Clinical Research Funding 2025-GSP-GG-36National Key Research and Development Program of China 2023YFC2506703National Natural Science Foundation of China 82473720National Natural Science Foundation of China T2541011Noncommunicable Chronic Diseases-National Science and Technology Major Project 2023ZD0503500Noncommunicable Chronic Diseases-National Science and Technology Major Project 2023ZD0504000
6 · The paper itself

Abstract

backgroundIt is still unclear how the risk of cardiovascular disease (CVD) changes across life course and the specific influence of body mass index (BMI) on risk trajectory.

methodsWe included 106,962 participants aged 35-74 from a Chinese longitudinal cohort during 1992 to 2021 with 4 repeated measurements. China-PAR (Prediction for Atherosclerotic Cardiovascular Disease Risk in China) equation was applied to calculate 10-year CVD risk. General additional mixed model and Joinpoint model were used to elaborate CVD risk trajectory and the potential benefits of normal BMI.

resultsThe 10-year CVD risk for Chinese adults increased from 1.11% [95% confidence interval (CI): 1.00%, 1.22%] to 14.87% (95%CI: 14.76%, 14.99%) dramatically between ages 35-74, with average CVD risk reaching moderate- and high-risk level at 53 and 65 years, respectively. Compared to overweight/obesity (BMI ≥ 25 kg/m

conclusionsThis study delineated cardiovascular risk trajectory, identifying critical intervention windows and demonstrating potential cardiovascular benefits of normal BMI, particularly in women.

Indexed as

Body Mass IndexCardiovascular DiseasesAdultAgedChinaEast Asian PeopleFemaleHeart Disease Risk FactorsHumansLongitudinal StudiesMaleMiddle AgedObesityRisk AssessmentBody mass indexCardiovascular benefitsCardiovascular riskTrajectory

Identifiers

PMID42098752
PMCPMC13321960

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.