ReviewCureus2026
Pharmacist-Led Deprescribing Interventions in Older Adults: A Systematic Review of Medication Appropriateness, Patient Safety, and Clinical Outcomes.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polypharmacy in older adults is associated with medication-related harm, including adverse drug events, drug-drug interactions, inappropriate prescribing, and hospitalization-related outcomes. This systematic review evaluated the effectiveness and safety of pharmacist-led deprescribing interventions in adults aged ≥65 years. The review was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement, and searches were conducted in PubMed, Embase, and Scopus for studies published from January 2020 to December 2024. Five studies met the inclusion criteria, including two randomized controlled trials and three quasi-experimental studies across inpatient, emergency department, and ambulatory settings. Pharmacist-led interventions were generally associated with reductions in potentially inappropriate medication use and improvements in medication appropriateness. Evidence regarding adverse drug events, hospital admissions/readmissions, mortality, and other major clinical outcomes remained limited and heterogeneous. Overall, pharmacist-led deprescribing appears feasible and may improve prescribing quality, but larger randomized studies with longer follow-up are needed to determine its effect on major clinical outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.