ArticleFrontiers in health services2025
Reduction of simultaneous ordering rate of high sensitivity C-reactive protein and erythrocyte sedimentation rate in a veteran affairs healthcare system.
Article in Frontiers in health services, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
It is widely recognized that the ESR (Erythrocyte Sedimentation Rate) and hs-CRP (C-Reactive Protein) are comparable inflammatory markers. In this reported veteran population, there is a significant correlation between the two assays. The simultaneous ordering of ESR and hs-CRP for evaluation of acute inflammation is unnecessary and wasteful. Various hospitals have implemented processes to reduce co-ordering habits through best practice advisories (BPAs) and/or educational interventions. In this retrospective study spanning twelve months, the Northern California Veteran Affairs Hospital System had a co-ordering rate of approximately 72% (number of hs-CRP orders with a co-ordered ESR compared to the total number of hs-CRP orders). After implementing a best practice ordering advisory and providing education to the clinical teams, there was a significant decrease in co-ordering of the assays (-34%,
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