ArticleFrontiers in endocrinology2026
Prognostic nutritional index, Naples prognostic score and Osaka prognostic score as predictors of acute respiratory distress syndrome in non-diabetes mellitus patients with sepsis: a loss of predictive efficacy of NPS and OPS in diabetes mellitus cohorts.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Prognostic Nutritional Index Predicts In-Hospital Mortality Among Patients withAntibiotics (Basel, Switzerland) · 2026Article
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Abstract
Background: Acute respiratory distress syndrome (ARDS) induced by sepsis is associated with uncontrolled immunoinflammatory responses and nutritional status. The purpose of this study was to explore the value of several prognostic scoring indices (Prognostic nutritional index (PNI), Naples prognostic score (NPS), and Osaka prognostic score (OPS)) in predicting ARDS risk among sepsis patients. Methods: 2089 sepsis patients were retrospectively enrolled, and divided into diabetes mellitus and non-diabetes mellitus groups based on the presence of comorbid diabetes mellitus. Baseline clinical data and laboratory test indicators at admission were collected, and the PNI, NPS, and OPS were calculated. The differences in PNI, NPS, and OPS between ARDS and non-ARDS patients were compared. Logistic regression analysis was performed to explore the associations of PNI, NPS, and OPS with ARDS in septic patients. Results: 1772 patients did not develop ARDS, whereas 317 cases with ARDS. PNI level in ARDS patients was lower than that in patients without ARDS ( Conclusions: PNI, NPS, and OPS were predictive indicators for ARDS risk in sepsis patients without diabetes mellitus; however, NPS and OPS lack corresponding predictive value in diabetes mellitus cohorts.
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