Evidence map›Paper›PMID 42100216›Full record

ArticleFrontiers in veterinary science2026

Synergistic effects of dietary RISCO-NUTRIFOUR probiotic on broiler performance, upregulation of intestinal immunoglobulin A and mucin-2 genes, enhancement of occludin expression, and downregulation of HSP70 under heat stress.

Abdulaziz A Al-Abdullatif, Maged A Al-Garadi, Mohammed M Qaid, Abdulkareem M Matar, Mohsen M Alobre, Mohammed A Al-Badwi, Elsayed O Hussein, Gamaleldin M Suliman

Abstract read
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In one paragraph

Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdulaziz A Al-AbdullatifDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Maged A Al-GaradiDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Mohammed M QaidDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Abdulkareem M MatarDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Mohsen M AlobreDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Mohammed A Al-BadwiDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Elsayed O HusseinDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Gamaleldin M SulimanDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heat stress (HS) remains a major challenge in poultry production, negatively impacting performance, gut health, and immune function. This study investigated the synergistic effects of a novel probiotic solution, RISCO-NUTRIFOUR (RNFS), on growth performance, immune modulation, and intestinal barrier integrity in heat-stressed broilers. A total of 288 Ross 308 broiler chicks were allocated to six dietary treatments, including RNFS at three inclusion levels [0.4, 0.2, and 0.1% "(4, 2, and 1 L RNFS/ton feed)"], 0.1%

Indexed as

broiler chickensheat stressHSP70 gene expressionprobiotics supplementationtight junction protein genes

Identifiers

PMID42100216
PMCPMC13143784

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.