Evidence map›Paper›PMID 42100324›Full record

ArticleFrontiers in pharmacology2026

Dual CD73/A

Katarina Mihajlovic, Milorad Dragic, Marija Adzic Bukvic, Teodora Martic, Ivana Stevanovic, Stéphane Vinit, Marêva Bleuzé, Arnaud Mansart, Lucille Adam, Nadezda Nedeljkovic

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Adenosine APharmaceuticals (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katarina MihajlovicCentre for Translational Neurosciences, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Belgrade, Serbia.
Milorad DragicCentre for Translational Neurosciences, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Belgrade, Serbia.
Marija Adzic BukvicCentre for Translational Neurosciences, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Belgrade, Serbia.
Teodora MarticCentre for Translational Neurosciences, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Belgrade, Serbia.
Ivana StevanovicMedical Faculty of the Military Medical Academy, University of Defense, Belgrade, Serbia.
Stéphane VinitUniversité Paris-Saclay, UVSQ, Inserm U1357, IMPROVE, Versailles, France.
Marêva BleuzéUniversité Paris-Saclay, UVSQ, InsermU1173, Infection et Inflammation (2I), Paris-Saclay, France.
Arnaud MansartUniversité Paris-Saclay, UVSQ, InsermU1173, Infection et Inflammation (2I), Paris-Saclay, France.
Lucille AdamUniversité Paris-Saclay, UVSQ, InsermU1173, Infection et Inflammation (2I), Paris-Saclay, France.
Nadezda NedeljkovicCentre for Translational Neurosciences, Department of General Physiology and Biophysics, Faculty of Biology University of Belgrade, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Excessive activation of the adenosine A Methods: Primary rat astrocytes were exposed to TNF-α, IL-1α, and C1q (TIC) to induce a neurotoxic reactive astrocyte (nRA) substate. Concomitant pharmacological inhibition of CD73 (APCP, 100 μM) and A Results: Dual CD73/A Discussion: These findings demonstrate that dual CD73/A

Indexed as

A2A receptor (A2AR)CD73neuroprotectionneurotoxic reactive astrocyte (nRA) substateoxidative stress

Identifiers

PMID42100324
PMCPMC13143737

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.