Evidence map›Paper›PMID 42100729›Full record

ArticleFrontiers in neuroscience2026

Oral administration of kratom leaf extract alleviates anxiety-like behavior, urinary bladder pain, voiding dysfunction, and bladder hypercontractility via attenuating muscarinic receptor response in male mice exposed to chronic water avoidance stress.

Sarunnuch Sattayachiti, Panida Chumpong, Dania Cheaha, Nattapon Rotpenpian, Ekkasit Kumarnsit, Nipaporn Konthapakdee

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarunnuch SattayachitiDivision of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
Panida ChumpongDivision of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
Dania CheahaDivision of Biological Science, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
Nattapon RotpenpianDepartment of Oral Biology and Occlusion, Faculty of Dentistry, Prince of Songkla University, Songkhla, Thailand.
Ekkasit KumarnsitDivision of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
Nipaporn KonthapakdeeDivision of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychological stress causes and deteriorates interstitial cystitis/painful bladder syndrome with urinary frequency, incontinence, bladder pain and urgency. The major alkaloid of kratom (

Indexed as

anxiety-like behaviorsbladder hyperactivitybladder painkratom leaf extractmitragyninepsychological stressvoiding pattern analysiswater avoidance stress

Identifiers

PMID42100729
PMCPMC13143891

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.