Evidence map›Paper›PMID 42101105›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance.

Wan-Qiong Huang, Tao Huang, Yiming Hao, Gui-Feng Huang, Yi-Lang Yan, Xin Fang, Ying Chen, Xiao-Long Wei, Wai-Lun Man, Wen-Xiu Ni

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wan-Qiong HuangDepartment of Pathology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, P. R. China.
Tao HuangDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, P. R. China.
Yiming HaoDepartment of Chemistry, Hong Kong Baptist University, Kowloon, HKSAR, P. R. China.
Gui-Feng HuangDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, P. R. China.
Yi-Lang YanDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, P. R. China.
Xin FangDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, P. R. China.
Ying ChenDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, P. R. China.
Xiao-Long WeiDepartment of Pathology, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, P. R. China.
Wai-Lun ManDepartment of Chemistry, Hong Kong Baptist University, Kowloon, HKSAR, P. R. China.ORCID https://orcid.org/0000-0001-5005-032X
Wen-Xiu NiDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong, P. R. China.ORCID https://orcid.org/0000-0002-2370-6300

Funding

Guangdong Basic and Applied Basic Research Foundation 2023A1515011759Guangdong Basic and Applied Basic Research Foundation 2023A1515220204Hong Kong Research Grants Council HKBU 22300222Key (Guangdong-Hong Kong Joint) Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province 2023B1212120011
6 · The paper itself

Abstract

Developing agents that disrupt the redox balance of tumor cells by simultaneously increasing reactive oxygen species (ROS) and decreasing antioxidants offers a promising approach in chemotherapy. Here, we present an isolable, interconvertible osmium redox pair, trans-[Os

Indexed as

Antineoplastic AgentsNeoplasmsOsmiumReactive Oxygen SpeciesAnimalsApoptosisCatalysisCell Line, TumorHumansMiceOxidation-ReductionAntineoplastic AgentsOsmiumReactive Oxygen Speciesbioinorganic chemistryimmunochemotherapyosmiumreactive oxygen speciesredox catalysis

Identifiers

PMID42101105
PMCPMC13336027

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.