ArticleRadiology. Imaging cancer2026
Time-dependent Diffusion MRI for Predicting Response to Induction Chemotherapy in Nasopharyngeal Carcinoma.
Article in Radiology. Imaging cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
14 authors.
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Abstract
Purpose To validate the reliability of time-dependent diffusion MRI (td-dMRI)-derived indicators in nasopharyngeal carcinoma (NPC) and determine whether microstructural parameters derived from td-dMRI can help noninvasively predict response to induction chemotherapy. Materials and Methods In this prospective study, participants with locally advanced NPC underwent pretreatment td-dMRI between December 2023 and February 2025. The data were randomly stratified and divided into a training set and an internal test set at a 7:3 ratio. According to Response Evaluation Criteria in Solid Tumors 1.1, all participants were classified as responders or nonresponders. Four imaging microstructural parameters with the limited spectrally edited diffusion-derived microstructural parameters (cell diameter
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