Evidence mapPaperPMID 42101363Full record

ArticleJournal of natural products2026

Prenylated Isoflavones Originating from East African Medicinal Plants Selectively Modulate the α-Glucosidase from

Kai Lüersen, Friederike Neuber, Eric Sperlich, Alexandra Kelling, Sarah von Chamier-Gliszczinski, Julia Greese, Taye B Demissie, Bernd Schmidt, Gerald Rimbach, Vaderament-Alexe Nchiozem-Ngnitedem

Abstract read
In one paragraph

Article in Journal of natural products, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kai LüersenInstitute of Human Nutrition and Food Science, University of Kiel, Kiel D-24118, Germany.ORCID 0000-0001-5812-1196
Friederike NeuberInstitute of Human Nutrition and Food Science, University of Kiel, Kiel D-24118, Germany.
Eric SperlichUniversity of Potsdam, Institut für Chemie, Karl-Liebknecht-Strasse 24-25, Potsdam-Golm, Potsdam D-14476, Germany.
Alexandra KellingUniversity of Potsdam, Institut für Chemie, Karl-Liebknecht-Strasse 24-25, Potsdam-Golm, Potsdam D-14476, Germany.
Sarah von Chamier-GliszczinskiUniversity of Potsdam, Institut für Chemie, Karl-Liebknecht-Strasse 24-25, Potsdam-Golm, Potsdam D-14476, Germany.
Julia GreeseUniversity of Potsdam, Institut für Chemie, Karl-Liebknecht-Strasse 24-25, Potsdam-Golm, Potsdam D-14476, Germany.
Taye B DemissieDepartment of Chemistry, Faculty of Science, University of Botswana, Gaborone, 00704, Botswana.
Bernd SchmidtUniversity of Potsdam, Institut für Chemie, Karl-Liebknecht-Strasse 24-25, Potsdam-Golm, Potsdam D-14476, Germany.ORCID 0000-0002-0224-6069
Gerald RimbachInstitute of Human Nutrition and Food Science, University of Kiel, Kiel D-24118, Germany.
Vaderament-Alexe Nchiozem-NgnitedemUniversity of Potsdam, Institut für Chemie, Karl-Liebknecht-Strasse 24-25, Potsdam-Golm, Potsdam D-14476, Germany.ORCID 0000-0001-8337-9260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nine naturally occurring prenylated isoflavones and three nonnatural analogues were synthesized for the first time. The 12 newly synthesized and 11 previously synthesized isoflavones were tested for their activity as modulators of

Indexed as

alpha-GlucosidasesGlycoside Hydrolase InhibitorsIsoflavonesPlants, MedicinalSaccharomyces cerevisiaeMolecular StructurePrenylationalpha-GlucosidasesGlycoside Hydrolase InhibitorsIsoflavones

Identifiers

PMID42101363
PMCPMC13200251

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.