Evidence map›Paper›PMID 42101639›Full record

ReviewArchives of microbiology2026

Insect immunity unveiled: exploring the molecular and cellular defenses against microbial threats.

Preena Makkar, Chandra Kant Singh, Nitin V, Parminder Kaur Narang, Kushneet Kaur Sodhi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Preena Makkar *Department of Zoology Sri Guru Tegh Bahadur Khalsa College, University of Delhi, Delhi, 110007, India.
Chandra Kant Singh *Department of Zoology, Ramjas College, University of Delhi, Delhi, 110007, India.
Nitin VDepartment of Zoology, University of Delhi, Delhi, 110007, India.
Parminder Kaur Narang *Department of Zoology Sri Guru Tegh Bahadur Khalsa College, University of Delhi, Delhi, 110007, India.
Kushneet Kaur Sodhi *Department of Zoology Sri Guru Tegh Bahadur Khalsa College, University of Delhi, Delhi, 110007, India. kushneetsodhi936@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insects, as diverse and ecologically dominant organisms, rely exclusively on innate immunity to defend against a wide array of microbial threats. This paper presents an integrative review of insect immune mechanisms, highlighting the molecular, cellular, and systemic components that underpin host defense. The immune response is orchestrated through physical barriers, cellular processes and humoral factors. Evolutionarily conserved pattern recognition receptors (PRRs) are essential to these processes. Emphasis is laid on pivotal functions of hemocytes, the significance of microbiome interactions in immune regulation, and the emerging influence of non-coding RNAs. Furthermore, the paper explores defensive symbiosis, environmental and evolutionary influences on immune dynamics, and applications in biotechnology and pest management. Model organisms, such as Drosophila melanogaster and Bombyx mori, serve as critical systems for unravelling innate immunity, with translational relevance to vertebrate immunology and vector control strategies. Understanding these mechanisms offers valuable insights into conserved immune pathways and holds promise for advancing strategies in human disease prevention, therapeutic innovation, and global health.

Indexed as

Immunity, InnateInsectaAnimalsDrosophila melanogasterHemocytesHost-Pathogen InteractionsInnate Immunity RecognitionMicrobiotaReceptors, Pattern RecognitionSymbiosisReceptors, Pattern RecognitionCellular defensesInsect, Innate immunityMolecular mechanisms

Identifiers

PMID42101639

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.