Evidence mapPaperPMID 42101771Full record

ArticleIrish journal of medical science2026

Utility of the 4-meter backward walking speed test in older adults with neurodegenerative diseases.

Kubra Altunkalem Seydi, Derya Kaya, Idil Yavuz, Alev Cam Mahser, Feyza Mutlay, Fatma Sena Dost, Ahmet Turan Isik

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Article in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Kubra Altunkalem SeydiDepartment of Geriatric Medicine, Ministry of Health Edirne Sultan Murat 1 State Hospital, Edirne, Turkey.
Derya KayaGeriatric Sciences Association, Izmir, Turkey. deryakaya29@gmail.com.ORCID http://orcid.org/0000-0002-5637-1308
Idil YavuzDepartment of Statistics, Faculty of Science, Dokuz Eylul University, Izmir, Turkey.
Alev Cam MahserGeriatric Sciences Association, Izmir, Turkey.
Feyza MutlayGeriatric Sciences Association, Izmir, Turkey.
Fatma Sena DostGeriatric Sciences Association, Izmir, Turkey.
Ahmet Turan IsikGeriatric Sciences Association, Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimLess is known about backward walking speed (BWS) in older adults. This study aims to establish a cutoff value for BWS to distinguish cognitively impaired individuals from healthy controls and to assess the association between backward walking slowing and risk of neurodegenerative diseases.

methods389 older patients, grouped into cognitively healthy (CH), amnestic mild cognitive impairment (aMCI), Alzheimer's disease (AD), Parkinson's disease (PD), and non-AD groups. BWS was measured using a standardized 4-meter protocol. Cognitive and functional status were evaluated via the comprehensive geriatric assessment. ROC analysis was used to determine the diagnostic threshold for BWS, and multinomial logistic regression was used to assess the associations.

resultsA BWS cutoff of 0.395 m/s effectively distinguished CH individuals from those with neurodegenerative diseases (AUC=0.723). After adjusting for age, each 0.1 m/s decrease in BWS was associated with 22% increased odds of having aMCI, 37% increased odds of AD, 28% increased odds of PD, and 59% increased odds of having non-AD dementia. BWS showed a positive association with global cognitive scores in patients with CH and aMCI (p< 0.05) and with semantic verbal fluency scores in those with AD and aMCI (p< 0.05).

conclusionBWS is associated with an increased risk of neurodegenerative diseases, which can cause cognitive impairment, and may help indicate individuals at risk of cognitive decline.

Indexed as

Alzheimer’s diseaseBackward walkingGaitParkinson’s disease

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.