ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026
Impact of catheter design on lesion dimensions during focal-bipolar pulsed field ablation: an in vitro potato model study.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPulsed field ablation (PFA) is a novel technique for pulmonary vein isolation (PVI) in the treatment of atrial fibrillation (AF). However, the impact of electrode type on lesion formation at fixed PFA parameters remains unknown. This study investigated differences in lesion characteristics when using a 4 mm non-irrigated catheter versus an open-irrigated flexible-tip catheter in focal-bipolar PFA in a potato model.
methodsPFA applications were performed in a potato model using a purpose-made PFA generator, applying both a solid-tip 4 mm non-irrigated catheter and an open-irrigated flexible-tip catheter under identical energy delivery parameters. After electroporation, potatoes were stained with triphenyltetrazolium chloride (TTC) to visualize lesion boundaries. Depth, diameter, and volume of the irreversibly electroporated zones were measured to assess the impact of each electrode type.
resultsA total of fifty PFA applications were performed - 25 with the 4 mm non-irrigated catheter and 25 with the open-irrigated flexible-tip catheter. The depth of the irreversible electroporation zone was significantly greater with the 4 mm non-irrigated catheter than with the irrigated electrode (1.7 ± 0.5 mm vs. 1.4 ± 0.7 mm, p = 0.03). The diameter of irreversible lesions created with the 4 mm electrode was 7 ± 1 mm, compared to 6 ± 1 mm with the irrigated electrode (p = 0.001), resulting in a total lesion volume of 46 ± 19 mm³ versus 30 ± 12 mm³, respectively (p = 0.0008).
conclusionThe use of a solid-tip 4 mm non-irrigated catheter in focal-bipolar PFA creates lesions with greater depth, volume and diameter compared to an open-irrigated flexible-tip catheter. Ablation catheter type significantly influences lesion spread during focal-bipolar PFA.
Indexed as
Identifiers
42101804What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.