ArticlePloS one2026
Comparative associations of body mass index and waist-to-height ratio with cardiometabolic and functional health risk markers in children aged 6-12 years - the Health Oriented Pedagogical Project (HOPP).
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundBody mass index (BMI) and waist-to-height ratio (WHtR) are widely used markers of adiposity in children, but their relative associations with cardiometabolic and functional health measures remain debated.
methodsWe analyzed data from children aged 6-12 years (n = 2297) in the Health Oriented Pedagogical Project (HOPP) with annual assessments from 2015-2020. Associations between BMI or WHtR and outcomes (body composition, blood lipids, blood pressure, physical activity, and cardiorespiratory fitness/endurance) were examined using linear mixed-effects models with repeated measures (random intercept for child; study year as the repeated factor). BMI and WHtR were evaluated in separate models.
resultsBoth BMI and WHtR were consistently associated with less favorable profiles across outcomes, including higher adiposity, lower fitness/endurance and MVPA, higher blood pressure, and a more adverse lipid profile (lower HDL and higher non-HDL cholesterol). Across most outcomes, differences between BMI- and WHtR-based models were modest; however, WHtR generally showed slightly stronger associations for lipid measures and fitness-related outcomes.
conclusionsBMI and WHtR demonstrate largely comparable associations with cardiometabolic and functional health measures in children aged 6-12 years. WHtR may provide complementary information on central adiposity and can be considered alongside BMI in pediatric screening and surveillance.
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