Evidence map›Paper›PMID 42102048›Full record

ArticleBrain and behavior2026

"Silent Echoes of the Day: Dream Content Analysis in Amyotrophic Lateral Sclerosis".

Alessandro Bombaci, Alessandra Giordano, Ilaria Lavalle, Alice Magnino, Andrea Calvo, Adriano Chiò, Alessandro Cicolin

Abstract read
In one paragraph

Article in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessandro BombaciNeurology Unit, IRCSS Policlinico San Donato, San Donato Milanese, Italy.
Alessandra GiordanoSleep Medicine Centre, "Rita Levi Montalcini" Department of Neuroscience, University of Torino, Turin, Italy.ORCID https://orcid.org/0000-0002-6394-6210
Ilaria LavalleSleep Medicine Centre, "Rita Levi Montalcini" Department of Neuroscience, University of Torino, Turin, Italy.
Alice MagninoSleep Medicine Centre, "Rita Levi Montalcini" Department of Neuroscience, University of Torino, Turin, Italy.
Andrea CalvoTurin ALS Centre, "Rita Levi Montalcini" Department of Neuroscience, University of Torino, Turin, Italy.
Adriano ChiòTurin ALS Centre, "Rita Levi Montalcini" Department of Neuroscience, University of Torino, Turin, Italy.
Alessandro CicolinTurin ALS Centre, "Rita Levi Montalcini" Department of Neuroscience, University of Torino, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the degeneration of upper and lower motor neurons, leading to muscle atrophy, weakness, and respiratory failure. Numerous studies evaluated the impact of diseases on dream content, and the dream content analysis may be considered an interesting tool in the study of the internalization of the consequences of significant life changes. The study of ALS patients' dream content has been mostly neglected in the literature. This study investigated the dream content in a population affected by ALS. MATERIAL AND

methodsWe evaluated all consecutive outpatients referred to our ALS Centre using a weekly diary of dreams. Dream contents were coded according to the Hall and Van de Castle coding system.

resultsSixty-eight patients completed the study. We collected 127 dreams (females 39.4%) (males 60.6%). Males showed a reduced presence of friends, anatomical elements, aggression, friendship, and sexuality. Instead, we found an increased presence of family members, situations in which the dreamer initiates aggressive action and familiar settings. In the female sample, we found a decreased presence of friends, aggressive and friendly elements, sex-related content, and misfortune, while an increase in animal content.

conclusionsOur results demonstrate that dream content in ALS patients differs from that of healthy subjects, and we noticed some gender differences among ALS patients. The dream content can offer insights into ALS patients' mental state and may improve clinicians' ability to support their patients during their therapeutic course.

Indexed as

Amyotrophic Lateral SclerosisDreamsAdultAgedFemaleHumansMaleMiddle AgedALSdreamneurodegenerationsleep

Identifiers

PMID42102048
PMCPMC13155465

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.