Evidence map›Paper›PMID 42102476›Full record

ArticlePoultry science2026

Dietary gallic acid supplementation alleviates LPS-induced inflammatory responses and intestinal barrier damage in chickens at an early age.

Taidi Xiong, Zhilong Chen, Mubashar Hassan, Yunmao Huang, Jinling Ye, Qiuli Fan, Cui Zhu, Shouqun Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Taidi XiongInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China; School of Animal Science and Technology, Foshan University, Foshan 528225, China.
Zhilong ChenInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China; Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Mubashar HassanInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China.
Yunmao HuangZhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Jinling YeInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China.
Qiuli FanInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China.
Cui ZhuSchool of Animal Science and Technology, Foshan University, Foshan 528225, China. Electronic address: zhucui@fosu.edu.cn.
Shouqun JiangInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Guangzhou 510640, China. Electronic address: jiangshouqun@gdaas.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to investigate the effects of dietary gallic acid (GA) supplementation on growth performance and intestinal barrier function of broiler chickens challenged with lipopolysaccharide (LPS). A total of 750 1-day-old "817" male crossbred broilers were randomly assigned to 5 treatment groups, with six replicates per group: basal diet (CON), basal diet following LPS-challenge (LPS), and basal diet supplemented with 150, 300, 450 mg/kg GA following LPS-challenge (GA150, GA300, and GA450). On days 14, 17, and 20, chickens in the LPS, GA150, GA300, and GA450 groups received intraperitoneal injections of LPS, while chickens in the CON group received the same dose of saline. The results showed that, compared with broilers in CON, dietary supplementation with GA eliminated the negative effects of LPS on reducing BW on day 21, as well as the 1 to 21d ADFI and ADG compared to broilers in CON group (P < 0.05). Compared with the LPS group, dietary supplementation with 300 and 450 mg/kg GA significantly upregulated the relative expression of superoxide dismutase1 (SOD1), and 150 mg/kg GA significantly upregulated the relative expression of glutathione peroxidase 1 (GPX1) in ileal mucosa. Compared with the LPS group, dietary GA supplementation significantly increased the percentages of CD3

Indexed as

ChickensGallic AcidInflammationPoultry DiseasesAnimal FeedAnimalsDietDietary SupplementsDose-Response Relationship, DrugIntestinal Barrier FunctionIntestinal MucosaLipopolysaccharidesMaleRandom AllocationGallic AcidLipopolysaccharidesAntioxidant capacityBroilerGallic acidIntestinal damageLipopolysaccharideMicrobiota

Identifiers

PMID42102476
PMCPMC13186026

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.