Evidence map›Paper›PMID 42104249›Full record

ReviewBMC anesthesiology2026

Rescue strategies combining ultra-protective ventilation and veno-venous ECMO in a patient with near-drowning-related severe ARDS: a case report and literature review.

Li Zhang, Zhekang Peng, Dingdeng Wang, Fei Tian, Xingguang Qu, Zhaohui Zhang, Gaosheng Zhou

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Li Zhang *Department of Critical Care Medicine, Yichang Central People's Hospital, The First College of Clinical Medical Science of China Three Gorges University, Yichang, 443000, China.
Zhekang Peng *Department of Critical Care Medicine, Yichang Central People's Hospital, The First College of Clinical Medical Science of China Three Gorges University, Yichang, 443000, China.
Dingdeng WangDepartment of Critical Care Medicine, Yichang Central People's Hospital, The First College of Clinical Medical Science of China Three Gorges University, Yichang, 443000, China.
Fei TianDepartment of Critical Care Medicine, Yichang Central People's Hospital, The First College of Clinical Medical Science of China Three Gorges University, Yichang, 443000, China.
Xingguang QuDepartment of Critical Care Medicine, Yichang Central People's Hospital, The First College of Clinical Medical Science of China Three Gorges University, Yichang, 443000, China.
Zhaohui ZhangDepartment of Critical Care Medicine, Yichang Central People's Hospital, The First College of Clinical Medical Science of China Three Gorges University, Yichang, 443000, China. zhangzhaohui0316@163.com.
Gaosheng ZhouDepartment of Critical Care Medicine, Yichang Central People's Hospital, The First College of Clinical Medical Science of China Three Gorges University, Yichang, 443000, China. gszhou2012@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrowning can lead to acute respiratory distress syndrome (ARDS), which is associated with high mortality and poses substantial clinical management challenges. Ultra-protective ventilation strategy combined with veno-venous extracorporeal membrane oxygenation (VV-ECMO) present a viable alternative, yet evidence supporting these strategies in drowning-related ARDS patients remains scarce. CASE PRESENTATION: This case report describes an 18-year-old female who experienced cardiac arrest following near-drowning. After the return of spontaneous circulation, the patient developed severe pulmonary edema leading to ARDS. VV-ECMO was initiated, resulting in a significant improvement in the Horowitz coefficient. Using a combination of VV-ECMO and an ultra-protective ventilation strategy with a lowest tidal volume of 2.8 ml/kg (predicted body weight, PBW), the patient's lung condition improved significantly. Static lung compliance rose from 11 ml/cm H₂O to 46 ml/cm H₂O. The patient was successfully weaned from VV-ECMO on Day 15, extubated on Day 27, and eventually discharged with no obvious pulmonary sequelae.

conclusionThe present case indicate that combining ultra-protective ventilation and VV-ECMO may be an effective approach for managing severe near-drowning-related ARDS by improving lung function and increasing the likelihood of successful extubation. This strategy minimizes ventilator-induced lung injury (VILI) while optimizing oxygenation, providing a new perspective for treating similar patients. Further studies are needed to validate its efficacy and optimize treatment protocols.

Indexed as

Extracorporeal Membrane OxygenationNear DrowningRespiration, ArtificialRespiratory Distress SyndromeAdolescentFemaleHumansPulmonary EdemaARDSCase reportNear-drowningUltra-protective ventilationVV-ECMO

Identifiers

PMID42104249
PMCPMC13321418

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.