Evidence map›Paper›PMID 42104645›Full record

ArticleCroatian medical journal2026

Antidepressant prescribing pattern in Croatia: a retrospective, longitudinal study from 2017 to 2022.

Katarina Gvozdanović, Roberto Mužić, Helena Orehovački, Danijela Štimac Grbić

Abstract read
In one paragraph

Article in Croatian medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katarina GvozdanovićKatarina Gvozdanović, Department of Pharmacoepidemiology, Teaching Institute of Public Health, Mirogojska cesta 16, 10000 Zagreb, Croatia, katarina.gvozdanovic@stampar.hr.
Roberto Mužić
Helena Orehovački
Danijela Štimac Grbić

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess antidepressant prescribing patterns in Croatia.

methodsThis retrospective study assessed electronic prescription patterns for antidepressants (Anatomical Therapeutic Chemical code N06A) in Croatia from 2017 to 2022. We collected data on annual prescription counts, drug types, drug utilization, utilization trends, indications, and patient demographics.

resultsOver six years, 8.66 million antidepressant prescriptions were issued to 415 328 patients in Croatian primary care. Utilization increased by 22.32% (from 22.4 to 27.4 defined daily doses per 1000 inhabitants per day) but remained below the European average. Selective serotonin reuptake inhibitors accounted for nearly 60% of prescriptions. Women and older adults (≥65 years) were the primary users.

conclusionDespite rising antidepressant use, Croatia lags behind other European countries, possibly due to high benzodiazepine use. The prescribing pattern highlights the need for targeted, evidence-based mental health policies. Special attention should be given to pediatric patients, the elderly, and patients affected by war-related trauma, while also exploring socioeconomic influences on prescribing practices.

Indexed as

Antidepressive AgentsDrug PrescriptionsDrug UtilizationPractice Patterns, Physicians'AdolescentAdultAgedChildCroatiaFemaleHumansLongitudinal StudiesMaleMiddle AgedPrimary Health CareRetrospective StudiesAntidepressive AgentsSelective Serotonin Reuptake Inhibitors

Identifiers

PMID42104645
PMCPMC13176931

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.