Evidence map›Paper›PMID 42109081›Full record

SynthesisTheScientificWorldJournal2026

Clinical Effectiveness of Traditional Polyherbal Formulations for Wound Healing: A Systematic Review and Meta-Analysis.

Samuel Abiodun Kehinde, Nurulhusna Awaeloh, Pinanong Na-Phatthalung, Siriwan Kantisin, Sasitorn Chusri

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in TheScientificWorldJournal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samuel Abiodun KehindeBiomedical Technology Research Group for Vulnerable Populations and the School of Health Science, Mae Fah Luang University, Muang Chiang Rai, Thailand, mfu.ac.th.ORCID https://orcid.org/0000-0003-3768-906X
Nurulhusna AwaelohThai Faculty of Allied Health Science, Nakhon Ratchasima College, Nakhon Ratchasima, Thailand.ORCID https://orcid.org/0009-0002-0752-2402
Pinanong Na-PhatthalungDivision of Hematology and Oncology, Icahn School of Medicine at Mount Sinai, New York, New York, USA, mountsinai.org.ORCID https://orcid.org/0000-0002-8162-4645
Siriwan KantisinOccupational Health and Safety Program, School of Health Science, Mae Fah Luang University, Chiang Rai, Thailand, mfu.ac.th.ORCID https://orcid.org/0009-0004-9538-5499
Sasitorn ChusriBiomedical Technology Research Group for Vulnerable Populations and the School of Health Science, Mae Fah Luang University, Muang Chiang Rai, Thailand, mfu.ac.th.ORCID https://orcid.org/0000-0002-7365-6890

Funding

Mae Fah Luang UniversityNational Science, Research, and Innovation Fund (NSRF) 682A05005
6 · The paper itself

Abstract

Chronic wounds, especially in diabetic patients, are difficult to manage because of delayed healing and high infection risk. Traditional polyherbal formulations, which are composed of multiple medicinal plants with synergistic effects, are widely used in wound care, but their clinical effectiveness has not been comprehensively synthesized. This study aimed to perform a systematic review and meta-analysis of randomized controlled trials (RCTs) assessing the effectiveness of traditional polyherbal formulations for wound healing. Databases were searched, and RCTs involving adults with wounds, where the intervention was traditional polyherbal formulation rather than a placebo, standard care, or other active treatments, were included. The meta-analysis was conducted via a random-effects model, and the certainty of evidence was evaluated via GRADE. Eight RCTs were included. The pooled mean difference for healing time favored polyherbal formulations (-3.28 days; 95%CI = -8.56 to 2.01) but was not statistically significant. Similarly, HbA1c reduction (-5.97%; 95%CI = -30.86 to 18.93) was not significantly different, with high heterogeneity (I

Indexed as

PhytotherapyPlant PreparationsPlants, MedicinalWound HealingHumansRandomized Controlled Trials as TopicTreatment OutcomePlant Preparationschronic woundsdiabetic ulcersherbal medicineinflammationmedicinal herbspolyherbaltissue regenerationwound healingwound management

Identifiers

PMID42109081
PMCPMC13158697

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.