Evidence map›Paper›PMID 42109124›Full record

ArticleHypertension (Dallas, Tex. : 1979)2026

Wrist-Measured Nighttime Home BP and Left Ventricular Hypertrophy: The WISDOM-HMOD Study.

Kazuomi Kario, Kenji Harada, Yusuke Ishiyama, Takeshi Fujiwara, Keisuke Narita, Yusuke Suzuki, Hiroyuki Mizuno, Ryosuke Komi, Naoko Tomitani, Satoshi Hoshide

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kazuomi KarioDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).ORCID 0000-0002-8251-4480
Kenji HaradaDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).ORCID 0000-0002-8920-1997
Yusuke IshiyamaDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).
Takeshi FujiwaraDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).ORCID 0000-0003-4151-2806
Keisuke NaritaDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).ORCID 0000-0002-2020-898X
Yusuke SuzukiDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).
Hiroyuki MizunoDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).ORCID 0000-0003-2266-0627
Ryosuke KomiKomi Internal Clinic, Tokyo, Japan (R.K.).
Naoko TomitaniDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).ORCID 0000-0002-1443-7073
Satoshi HoshideDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan (K.K., K.H., Y.I., T.F., K.N., Y.S., H.M., N.T., S.H.).ORCID 0000-0001-7541-5751

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNighttime blood pressure (BP) assessed by ambulatory BP monitoring is linked to left ventricular hypertrophy and its sequelae, including heart failure. However, the association between nighttime BP measured by a wrist-type oscillometric home BP monitor-designed to be less intrusive than brachial devices-and left ventricular hypertrophy remains unclear.

methodsThe WISDOM-HMOD study (Wrist ICT-based Sleep and Circadian Blood Pressure Monitoring Program-Hypertension-Mediated Organ Damage), a substudy of the WISDOM-Night study, included 1218 patients with hypertension or heart failure (mean age, 67.2±12.0 years; 53.9% men) who were recruited between 2021 and 2024. Nighttime BPs (2:00, 3:00, and 4:00 am and 4 hours after bedtime) and morning/evening BPs over 7 days were measured using a wrist-type home BP monitor (HEM9601T; Omron).

resultsThe average nighttime systolic/diastolic BP was 110.5±13.0/63.5±8.8 mm Hg, and 70.4% of patients had well-controlled nighttime BP (<120/70 mm Hg). The average left ventricular mass index assessed by echocardiography was 90.1±23.6 g/m

conclusionsThis study shows that nighttime home BP measured using a less sleep-disturbing wrist-type device is an independent risk factor for left ventricular hypertrophy and its potential sequelae, including new-onset or recurrent heart failure, with high-risk nighttime BP thresholds differing by sex.

Indexed as

Blood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmHypertensionHypertrophy, Left VentricularAgedFemaleHeart FailureHumansMaleMiddle AgedWristblood pressureheart failurehumansrisk factors

Identifiers

PMID42109124
PMCPMC13275078

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.