ReviewReviews in cardiovascular medicine2026
Plaque Progression and Rupture in Obstructive Coronary Artery Disease: A Review of Current Imaging Modalities.
Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atherosclerotic plaque progression and rupture are the chief determinants of acute coronary syndromes and long-term outcomes in obstructive coronary artery disease (CAD). Residual risk persists despite intensive low-density lipoprotein-lowering and contemporary secondary prevention, because vascular inflammation and microstructural frailty often remain unresolved. At the bedside, the lesion that precipitates infarction is seldom the tightest but rather the most unstable. This review integrates the mechanistic chain, from endothelial dysfunction and retention/oxidation of apolipoprotein B lipoproteins to maladaptive innate and adaptive immunity, failed efferocytosis with necrotic core expansion, and biomechanical forces that thin and fatigue the fibrous cap, with their corresponding
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.