Evidence mapPaperPMID 42110889Full record

SynthesisAlpha psychiatry2026

Effectiveness of Computerized Cognitive Remediation Therapy on Executive Functions and Clinical Symptoms in Children and Adolescents With ADHD: A Meta-Analysis of Randomized Controlled Trials.

Junrong Ye, Yuhan Zhang, Na Ma, Tian Zhou, Lexin Yuan, Yanheng Wei, Jinrong Li, Xueyu Zheng, Dingjie Liu, Jianxiong Guo and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Alpha psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Junrong YeDepartment of Nursing Administration, Department of Social Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, 510370 Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0003-0301-9738
Yuhan ZhangGuangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, 510370 Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0001-5913-6370
Na MaGuangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, 510370 Guangzhou, Guangdong, China.
Tian ZhouDepartment of Nursing Administration, Department of Social Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, 510370 Guangzhou, Guangdong, China.
Lexin YuanDepartment of Nursing Administration, Department of Social Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, 510370 Guangzhou, Guangdong, China.
Yanheng WeiDepartment of Nursing Administration, Department of Social Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, 510370 Guangzhou, Guangdong, China.
Jinrong LiGuangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, 510370 Guangzhou, Guangdong, China.
Xueyu ZhengGuangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, 510370 Guangzhou, Guangdong, China.
Dingjie LiuGuangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, 510370 Guangzhou, Guangdong, China.
Jianxiong GuoGuangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, 510370 Guangzhou, Guangdong, China.
Aixiang XiaoDepartment of Nursing Administration, Department of Social Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, 510370 Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-6094-2903

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This meta-analysis of randomized clinical trials (RCTs) aimed to determine whether computer-assisted cognitive remediation therapy (CCRT) is a feasible adjunctive treatment to improve executive function and clinical symptoms in adolescents and children with attention deficit hyperactivity disorder (ADHD). Methods: We systematically searched 9 English and Chinese databases from database inception until May 2025. Randomized controlled trials investigating CCRT in children and adolescents with ADHD were collected. The risk of bias was assessed using the Cochrane Collaboration's tool for assessing risk of bias (RoB 2.0) and the Jadad Scale. Standardized mean differences in post-intervention data were calculated using RevMan 5.4 software. This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered on the International Prospective Register of Systematic Reviews (PROSPERO) platform. Results: This review included 17 RCTs comprising 1087 cases. In the CCRT intervention groups, there was a significant decrease in overall executive function (standardized mean difference (SMD) = -0.23; 95% CI = [-0.45, -0.01]; Conclusion: CCRT played an important role in improving specific executive functions and attention symptoms in children and adolescents with ADHD. However, high-quality research is needed to validate these preliminary findings. The PROSPERO Registration: CRD42024619958, https://www.crd.york.ac.uk/PROSPERO/view/CRD42024619958.

Indexed as

attention deficit disorder with hyperactivityclinical symptomscognitive remediationcomputer-assisted therapyexecutive functionsmeta-analysis

Identifiers

PMID42110889
PMCPMC13156065

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.