Evidence mapPaperPMID 42112130Full record

ReviewJournal of ginseng research2026

Natural compounds for diabetes-related wounds or ulcers therapy: Evidence from preclinical and clinical studies.

Jia Teng, Guanchi Yan, Ming Yang, Shuangyue Wang, Yuezhu Zhao, Yanyan Wang, Jia Mi

Abstract readReview
In one paragraph

Review in Journal of ginseng research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jia TengCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.
Guanchi YanThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130021, China.
Ming YangThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130021, China.
Shuangyue WangThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130021, China.
Yuezhu ZhaoThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130021, China.
Yanyan WangThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130021, China.
Jia MiThe Affiliated Hospital to Changchun University of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes-related wounds or ulcers are one of the complications of diabetes that can cause a variety of functional losses. Treatment of diabetic skin ulcer (DSU) focuses on alleviating foot pressure and enhancing local circulation. Despite the availability of these treatments, the number of drugs for wound application is limited. In recent years, natural compounds obtained from plants have demonstrated positive effects on DSU and have effective in preclinical and clinical studies. Purpose: The objective of the study was to assess the diabetes-related wounds or ulcers of natural compounds and the potential mechanisms. Study design: and Methods: The study searched PubMed database up to January 2025. Results: In the review, the efficacy and safety of natural compounds in treating diabetes-related wounds or ulcers are summarized from 42 preclinical and 13 clinical studies. Conclusion: Overall, these preclinical and clinical studies advocate for the use of natural compounds in diabetes-related wounds or ulcers, indicating that ursolic acid, paeoniflorin, and

Indexed as

Clinical studiesDiabetes-related wounds or ulcersNatural compoundsPreclinical studiesTraditional medicines

Identifiers

PMID42112130
PMCPMC13149912

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.