Evidence map›Paper›PMID 42112300›Full record

ArticleIranian journal of microbiology2026

Incidence, microbial profile and antimicrobial resistance trends of CLABSI in adult ICUs: a longitudinal prospective study.

Gargee Anand, Asim Sarfraz, Bhaskar Thakuria, Prathyusha Kokkayil, Binod Kumar Pati

Abstract read
In one paragraph

Article in Iranian journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gargee AnandDepartment of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Asim SarfrazDepartment of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Bhaskar ThakuriaDepartment of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Prathyusha KokkayilDepartment of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India.
Binod Kumar PatiDepartment of Microbiology, All India Institute of Medical Sciences, Patna, Bihar, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Central line-associated bloodstream infections (CLABSIs) remain a major cause of healthcare-associated mortality, prolonged hospitalization, and increased healthcare costs, especially in resource-poor settings where surveillance data are scarce. This study aimed to determine CLABSI incidence, risk factors, causative organisms, and antimicrobial resistance (AMR) patterns across adult intensive care units (ICUs). Materials and Methods: A prospective longitudinal study was conducted amongst 200 adult ICU patients with central line (CL) in-situ for >2 calendar days. CLABSI surveillance followed definitions by The Centers for Disease Control and Prevention, National Healthcare Safety Network. Microbiological identification and antimicrobial susceptibility testing were performed according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: The overall CLABSI incidence was 19.25/1,000 catheter days. CLABSI patients demonstrated significantly extended hospitalization (20.22 vs 9.09 days, p<0.001) and CL duration (16.17 vs 7.85 days, p<0.001). Femoral lines had the highest infection rate (42.85%). The median time from CL insertion to the onset of CLABSI was 7.5 days. Gram-negative organisms predominated (75%), with Conclusion: The study demonstrates high CLABSI incidence and alarming levels of AMR, underscoring the urgent need for strengthening infection prevention practices and antimicrobial stewardship in ICUs.

Indexed as

Antimicrobial resistanceBloodstream infectionCatheter-associated infectionsCentral venous catheterHealthcare associated infections

Identifiers

PMID42112300
PMCPMC13156819

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.