Evidence mapPaperPMID 42115409Full record

ArticleOncogene2026

Cannabinoid CB

Marta Seijo-Vila, Sofía A Balsinde, Sandra Blasco-Benito, Isabel Tundidor, María Rubert-Hernández, Ana Montero-Calle, Rodrigo Barderas, Laura E Kilpatrick, Simon Platt, Noemi Karsai and 23 more

Abstract read
In one paragraph

Article in Oncogene, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Marta Seijo-VilaDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.
Sofía A BalsindeDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.
Sandra Blasco-BenitoHospital del Mar Research Institute (IMIM), Barcelona, Spain.
Isabel TundidorDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.
María Rubert-HernándezDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.
Ana Montero-CalleChronic Disease Programme (UFIEC), Instituto de Salud Carlos III, Madrid, Spain.
Rodrigo BarderasChronic Disease Programme (UFIEC), Instituto de Salud Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0003-3539-7469
Laura E KilpatrickCentre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands, Nottingham, UK.
Simon PlattCentre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands, Nottingham, UK.ORCID http://orcid.org/0000-0002-8418-3646
Noemi KarsaiCentre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands, Nottingham, UK.ORCID http://orcid.org/0009-0000-3948-4071
Isabel PhilpsCentre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands, Nottingham, UK.
Olga M AntónDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0003-4916-5319
Déborah Gómez-DomínguezGene Therapy Unit, Instituto de Investigación de Enfermedades Raras y Departamento de Desarrollo de Medicamentos y Terapias Avanzadas, Instituto de Salud Carlos III, Madrid, Spain.
Ignacio Pérez de CastroGene Therapy Unit, Instituto de Investigación de Enfermedades Raras y Departamento de Desarrollo de Medicamentos y Terapias Avanzadas, Instituto de Salud Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0002-8822-8274
Carmen González-LoisDepartment of Pathology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Diego García-FresnadilloDepartment of Pathology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Gala Silvestre-EgeaDepartment of Pathology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Antonio J Sánchez-LópezNeuroimmunology Unit, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Madrid, Spain.
Esther Ramírez-MedinaDepartment of Gynecology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
María Catalina Rivas PrietoDepartment of Gynecology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Belén Almoguera Pérez-CejuelaDepartment of Gynecology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Luis MansoInstituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
Sandra ZazoPathology Department, IIS-Hospital Universitario Fundación Jiménez Díaz-CIBERONC, Madrid, Spain.
Noemí López-EjedaDepartment of Biodiversity, Ecology and Evolution, Faculty of Biological Sciences, Nutritional Epidemiology (EPINUT) Research Group, Complutense University of Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0003-1310-0134
Francisco Palomino-DuqueDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.
María Turienzo-DuránDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.
Nuria G Martínez-IllescasDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.
María Salazar-RoaDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.
Sonia Castillo-LluvaDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0001-5357-7178
Stephen J HillCentre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, The Midlands, Nottingham, UK.ORCID http://orcid.org/0000-0002-4424-239X
Manuel GuzmánDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0001-7475-118X
Eduardo Pérez-GómezDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain. eduperez@ucm.es.ORCID http://orcid.org/0000-0003-0160-5565
Cristina SánchezDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Complutense University of Madrid, Madrid, Spain. macsanch@ucm.es.ORCID http://orcid.org/0000-0002-1428-3078

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquired or innate lack of response to standard HER2-targeted therapies remains a clinical issue in patients with HER2-positive breast cancer. Here, we investigated the role of the cannabinoid CB

Indexed as

Breast NeoplasmsDrug Resistance, NeoplasmErb-b2 Receptor Tyrosine KinasesReceptor, Cannabinoid, CB2TrastuzumabAnimalsAntineoplastic Agents, ImmunologicalCell Line, TumorErbB ReceptorsFemaleHumansMiceSignal TransductionXenograft Model Antitumor AssaysAntineoplastic Agents, ImmunologicalCNR2 protein, humanERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesErbB ReceptorsReceptor, Cannabinoid, CB2Trastuzumab

Identifiers

PMID42115409
PMCPMC13269139

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.