Evidence map›Paper›PMID 42116402›Full record

SynthesisMedicine2026

Curative effect of acupuncture combined with Chinese medicine on cancer pain: Systematic review and meta-analysis.

Guocheng Xue, Siqi Zhang, Afeng Miao, Yubo Teng, Hao Ming, Miao Zhang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guocheng XueHeilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.ORCID 0009-0000-1243-308
Siqi ZhangAcupuncture and Moxibustion Consulting Room No. 10, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Afeng MiaoHeilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Yubo TengHeilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Hao MingHeilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Miao ZhangAcupuncture and Moxibustion Consulting Room No. 10, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.ORCID 0000-0002-4421-7100

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer and cancer pain caused by treatment have brought great challenges. With the increasing number of papers on the treatment of cancer pain with acupuncture combined with Chinese medicine, this paper aims to evaluate the evidence of the association of acupuncture combined with Chinese medicine with reduction in cancer pain.

methodFour English databases and 4 Chinese databases were systematically searched from the establishment of the database to September 18, 2024. Randomized clinical trials that compared acupuncture combined with Chinese medicine with acupuncture alone, analgesic therapy, or other usual care for cancer pain were included. Data were screened and extracted independently using predesigned forms. The quality of randomized controlled trials (RCTs) was appraised with the Cochrane Collaboration risk of bias tool with Rvman 5.4 software. According to the different types of data,count data used risk ratioas the effect sizes, and Measurement data used Mean difference (MD)as the effect sizes and standardized MD.

resultsTen RCTs (comprising 884 participants) were incorporated into the systematic review, with data from all ten trials included in the meta-analysis. Findings from 7 of the trials indicated that the combination of acupuncture and Chinese medicine, when compared to other forms of care, led to a decrease in pain intensity. A good analgesic efficacy was seen by using the acupuncture combined with Chinese medicine in 6 RCTs (MD, 1.22 points; 95% confidence interval [CI], 1.12 to 1.32;Ⅰ2 = 13%). Two RCTs showed that acupuncture combined with Chinese medicine and tertiary analgesic therapy could shorten the onset time of analgesics(MD, -14.82 points;95% CI, -16.80 to -12.82;Ⅰ2 = 0%); and 3 RCTs increased the duration of analgesia(MD, 2.40 points;95% CI, 2.01 to 3.82;Ⅰ2 = 95%). An improvement in the quality of life of the cancer patients was seen when acupuncture combined with Chinese medicine was used in 5 RCTs (MD, 4.68 points;95% CI, 3.69 to 5.66;Ⅰ2 = 0%).

conclusionThe systematic review and meta-analysis conducted that a significant reduction in cancer pain was observed in patients who received acupuncture combined with Chinese medicine, compared to those who received other treatment.

Indexed as

Acupuncture TherapyCancer PainDrugs, Chinese HerbalMedicine, Chinese TraditionalCombined Modality TherapyHumansPain ManagementRandomized Controlled Trials as TopicTreatment OutcomeDrugs, Chinese Herbalacupuncture combined with Chinese medicinecancer painintegrative medicine of traditional Chinese medicine

Identifiers

PMID42116402
PMCPMC13166862

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.