ArticleDiabetes, obesity & metabolism2026
Body Mass Index and All-Cause, Cancer, and Cardiovascular Mortality in Adults Aged 16-50 Years With and Without Type 2 Diabetes: An Analysis of Primary Care Records in England.
Article in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
aimsTo examine the association between body mass index (BMI) and risk of all-cause, cancer, and cardiovascular diseases (CVD) mortality among adults aged 16-50 years with and without type 2 diabetes (T2D). MATERIALS AND
methodsWe conducted a retrospective matched cohort study using primary care records from the Clinical Practice Research Datalink (CPRD) linked to Hospital Episode Statistics (HES) and Office for National Statistics (ONS) mortality records. Individuals aged 16-50 years with T2D were matched (1: up to 10) to those without T2D by year of birth, sex, and general practice. Using flexible parametric survival models and competing risk approaches, we estimated hazard ratios (HRs) and 10-year cumulative incidences of all-cause and cause-specific mortality adjusted for confounders.
resultsA total of 384 787 individuals were included, of whom 86 606 (22.5%) lived with T2D (median age at diagnosis, 44.0 years). The associations between BMI and all-cause mortality, as well as cause-specific mortality, exhibited a U-shaped pattern, with the nadir occurring at a BMI of 29.3 kg/m
conclusionsThe excess risk of mortality associated with T2D was greatest at lower BMI, where absolute risk estimates were high.
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