ArticleNature neuroscience2026
Individual differences in prosocial learning are represented in the hippocampal dorsal CA1.
Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Individual differences in prosocial learning are represented in the hippocampal dorsal CA1.Nature neuroscience · 2026Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Animals can learn about danger by observing conspecifics, but whether and how they acquire behaviors through positive affective states of others is not understood. Here we show that by observing a demonstrator, mice learn to take actions that benefit others and that are goal-directed and flexible. Chemogenetic silencing experiments showed that activity in hippocampal dorsal CA1 (dCA1) was required for observers to learn action-outcome associations in a social context. Fiber photometry recordings revealed inter-individual differences in dCA1 activity patterns during observation that tracked the observer's subsequent prosocial or selfish behavioral propensities. Optogenetic manipulations demonstrated that the dCA1 is key during observation and can orient a mouse's actions toward prosocial or selfish choices in future interactions. Our study provides a mouse model of social transmission of knowledge that guides prosocial behavior and that may be relevant for studying disorders in which the ability to learn from others' actions is compromised.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.