Evidence map›Paper›PMID 42121202›Full record

ArticleBMC health services research2026

HIV pre-exposure prophylaxis service delivery among young women at increased risk for HIV acquisition in South Africa: a time-and-motion study.

Rahel Dawit, Chitra Singh, Nombuso Matenjwa, Nosipho Dladla, Lillian Shipp, Mfezi Mcingana, Jenny Mcloughlin, Sharmistha Mishra, Joel Steingo, Amrita Rao and 4 more

Abstract read
In one paragraph

Article in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rahel DawitDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD, 21205, USA. rdawit1@jhu.edu.
Chitra SinghTB HIV Care, Pietermaritzburg, South Africa.
Nombuso MatenjwaKey Populations Programme, TB HIV Care, Durban, South Africa.
Nosipho DladlaKey Populations Programme, TB HIV Care, Durban, South Africa.
Lillian ShippDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD, 21205, USA.
Mfezi McinganaTB HIV Care, Cape Town, South Africa.
Jenny McloughlinTB HIV Care, Cape Town, South Africa.
Sharmistha MishraDepartment of Medicine, University of Toronto, Toronto, ON, Canada.
Joel SteingoTB HIV Care, Cape Town, South Africa.
Amrita RaoDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD, 21205, USA.
Joseph G RosenDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Stefan BaralDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD, 21205, USA.
Harry HauslerTB HIV Care, Cape Town, South Africa.
Sheree R SchwartzDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD, 21205, USA.

Funding

Johns Hopkins HIV Epidemiology and Prevention Sciences Training ProgramT32AI102623 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta · 2013 to 2026
$5.3M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Optimizing PrEP implementation and effectiveness among women at high risk for HIV acquisition in South AfricaR01MH121161 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SCHWARTZ, SHEREE RENAE · 2020 to 2024
$3.1M
NIAID NIH HHS T32 AI102623NIMH NIH HHS R01 MH121161NIMH NIH HHS R01MH121161NIMH NIH HHS R25 MH083620NIMH NIH HHS R25MH083620Tier 2 Canada Research Chair in Mathematical Modeling and Program Science CRC No. 950-232643
6 · The paper itself

Abstract

backgroundPrEP uptake and continuation among women in sub-Saharan Africa, including adolescent girls, young women (AGYW), and female sex workers (FSW), remains suboptimal. Societal costs, like lost wages and time, are potential barriers. This study assessed the time and resources spent by patients and provider for PrEP-related care including HIV testing, STI screening, PrEP counseling, and prescription management of PrEP among AGYW and FSW in South Africa, exploring factors that may affect PrEP uptake and continuation.

methodsWe conducted a cross-sectional time and motion study, representing a quantitative method used to assess the duration required to complete a defined series of tasks, at 13 decentralized PrEP service sites across nine districts in South Africa. The study measured time spent by clients (AGYW and FSW) receiving PrEP services and by healthcare providers delivering care. Wilcoxon rank-sum tests compared service durations, and opportunity costs (wages lost due to time receiving PrEP services) were estimated for all FSW.

resultsThe study included 148 participants (40% AGYW, 60% FSW). The median time for PrEP services was 25 min (IQR: 14-38). AGYW spent a median of 33 min (IQR: 21-53.5), and FSW spent 22 min (IQR: 13-33), (p = 0.0014). Time was longer for initiation visits (41 min) than refill visits (20 min) (p < 0.0001). Moreover, the median opportunity cost for FSW was 240 ZAR (IQR: 139-358). Lastly, providers spent 13.5-21 min on initiations and 9-27 min on refills.

conclusionsDespite free PrEP access, time and wage costs are significant barriers. Reducing the time commitments could enhance PrEP continuation for AGYW and FSW, though additional strategies for client support and counseling may be needed. Ultimately, improving the efficiency of PrEP delivery may boost PrEP continuation for marginalized women in South Africa.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisAdolescentAdultCross-Sectional StudiesFemaleHumansSex WorkersSouth AfricaTime and Motion StudiesYoung AdultAnti-HIV AgentsAdolescent girls and young womenFemale sex workersOpportunity costPre-exposure prophylaxisSouth AfricaTime-motion study

Identifiers

PMID42121202
PMCPMC13340240

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.