Evidence map›Paper›PMID 42122010›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Cerebral Venous Thrombosis: Pathophysiologic Insights, Clinical Evaluation Tools, and Novel Therapeutic Strategies.

Min Li, Qiqi Cui, Xiaogang Gao, Xuefan Yao, Ran Meng, Xunming Ji, Juexian Song

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Min LiDepartment of Neurology, Xuanwu Hospital Capital Medical University, Beijing 100053, China.ORCID 0000-0002-3842-9596
Qiqi CuiDepartment of Neurology, Xuanwu Hospital Capital Medical University, Beijing 100053, China.ORCID 0009-0003-1549-1762
Xiaogang GaoDepartment of Medicine, Tianjin Huanhu Hospital, Tianjin 300350, China.
Xuefan YaoDepartment of Neurology, Xuanwu Hospital Capital Medical University, Beijing 100053, China.
Ran MengDepartment of Neurology, Xuanwu Hospital Capital Medical University, Beijing 100053, China.
Xunming JiDepartment of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing 100053, China.ORCID 0000-0002-0527-2852
Juexian SongDepartment of Neurology, Xuanwu Hospital Capital Medical University, Beijing 100053, China.

Funding

National Natural Science Foundation of China 82401527
6 · The paper itself

Abstract

Cerebral venous thrombosis (CVT) is a rare but potentially life-threatening subtype of stroke, characterized by thrombus formation within the dural venous sinuses and cerebral veins. Recent advances have deepened our understanding of CVT pathophysiology, highlighting a multifactorial process that encompasses thrombus initiation, subsequent thrombus propagation, venous hypertension with blood-brain barrier disruption, and secondary parenchymal brain injury. Comprehensive clinical assessment, including diagnosis and differential diagnosis, disease severity scores, imaging-based metrics, and prognostic scoring systems, enables accurate evaluation and risk stratification. Emerging therapeutic strategies, including direct oral anticoagulants, corticosteroids for selected patients, natural-origin agents, immunomodulatory therapy, endovascular treatment, optic nerve sheath fenestration, and neuromodulation, provide novel and alternative options for the management of CVT. This review provides a comprehensive overview of CVT pathophysiology, clinical assessment tools, and novel therapeutic strategies to guide clinical decision-making and inform future research.

Indexed as

cerebral venous thrombosisdiagnosisevaluation toolsnovel therapypathophysiology

Identifiers

PMID42122010
PMCPMC13163386

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.