Evidence mapPaperPMID 42123127Full record

ReviewJournal of clinical medicine2026

SGLT2 Inhibitors in Clinical Practice: Cardiorenal Benefits and Risk of Fungal Infections-A Nephrologist's Perspective.

Wiktoria Andryszkiewicz, Zuzanna Cichowska, Maria Kręcicka, Sławomir Zmonarski

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wiktoria AndryszkiewiczFaculty of Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0009-0004-1827-6387
Zuzanna CichowskaFaculty of Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Maria KręcickaFaculty of Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0009-0001-7490-0832
Sławomir ZmonarskiDepartment of Nephrology, Transplantation Medicine and Internal Diseases, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0002-0764-4939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

People affected by diabetes mellitus (DM), chronic kidney disease (CKD), or heart failure are often prescribed sodium-glucose cotransporter-2 inhibitors (SGLT2is) as a method of treatment. These drugs favorably affect glucose metabolism, as patients taking them have lower serum glucose levels. Another promising positive impact is protection against microvascular damage, cardiovascular disease, and chronic kidney disease. Nevertheless, fungal infections, urinary tract infections, and ketoacidosis are the adverse effects that might happen during the SGLT2i treatment. Fungal infections are more common among patients treated with these medications, including vulvovaginal Candidiasis in women and balanitis or balanoposthitis in men. Given the difficulty of treating fungal infections in patients with co-occurring diseases, we recommend that ongoing supervision of patients treated with SGLT2i include prevention and early detection of fungal infections.

Indexed as

candiduriadiabetic kidney diseasegenital mycotic infectionSGLT2 inhibitorsurinary tract infection

Identifiers

PMID42123127
PMCPMC13164553

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.