ArticleMolecules (Basel, Switzerland)2026
Seasonal Variation of a New Brazilian Greenish-Brown Propolis Type: Chemical Composition and Antioxidant, Antimicrobial, and Antileishmanial Activities.
Emanoel Guilhermino da Silva, Arthur Luy T Ferreira Borges, João Victor L de Oliveria, Rodrigo J Nunes Calumby, Salvana P Manso Costa, Pierre Barnabé Escodro, Isabel Cristina Celerino de Moraes Porto, Ana Paula do Nascimento Prata Lins, Maria Aline B Fidelis de Moura, Camila B Dornelas and 7 more
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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5 · Who and what moneyAuthors and funding
17 authors.
Emanoel Guilhermino da SilvaPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0009-0002-3131-1437 Arthur Luy T Ferreira BorgesPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0001-5934-2652 João Victor L de OliveriaPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0002-8233-5722 Rodrigo J Nunes CalumbyPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0002-2313-5552 Salvana P Manso CostaPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0003-0055-1219 Pierre Barnabé EscodroPostgraduate Program of Veterinary Science, CECA, Federal University of Alagoas, Viçosa 57700-000, Alagoas, Brazil.ORCID 0000-0002-9409-660X Isabel Cristina Celerino de Moraes PortoPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0003-0908-7424 Ana Paula do Nascimento Prata LinsPostgraduate Program of Plants Protection, CECA, Federal University of Alagoas, Rio Largo 57100-000, Alagoas, Brazil.ORCID 0000-0001-7922-8355 Maria Aline B Fidelis de MouraPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0002-8068-8946 Camila B DornelasPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0002-2268-2650 Johnnatan Duarte de FreitasPostgraduate Program of Material Science, Center of Technology, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0002-6977-3322 Regianne U KamiyaPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0002-4854-4408 Lara Mendes AlmeidaPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0002-9027-5221 Louisianny Guerra da RochaLaboratory of Parasitology, Centre of Biosciences, Federal University of Rio Grande do Norte, Lagoa Nova, Natal 59078-970, Rio Grande do Norte, Brazil.ORCID 0000-0002-4307-2798 Edmilson Rodrigues da Rocha JuniorPostgraduate Program of Chemistry and Biotechnology, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceio 57072-900, Alagoas, Brazil.ORCID 0000-0002-1358-5031 Marília O F GoulartPostgraduate Program of Chemistry and Biotechnology, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceio 57072-900, Alagoas, Brazil.ORCID 0000-0001-9860-3667 Ticiano Gomes do NascimentoPostgraduate Program of Pharmaceutical Science, Institute of Pharmaceutical Science, Federal University of Alagoas, Maceio 57072-970, Alagoas, Brazil.ORCID 0000-0002-3856-8764 Funding
FAPEAL, Edital 02/2022 Support to Research in Post-Graduate E:60030.0000002389/2022FAPEAL, Edital 11/2022 Support to Pos-Doctor Junior E:60030.0000000327/2023Federal University of Alagoas 304765/2025-2
6 · The paper itselfAbstract
Propolis is a natural product of honey bees whose chemical composition is influenced by different plant species and environmental factors, resulting in diverse biological activities. A new propolis type, the greenish-brown propolis (GBPUP), was identified in the northeast of Brazil. This study aimed to evaluate the influence of seasonal variation in the chemical composition of GBPUP extracts over a 12-month period. LC-ESI-Orbitrap-FTMS and UFLC-DAD-UV-Vis revealed a chemical composition with some differences to that of Brazilian green propolis, with pinocembrin as the major compound, followed by galangin, pinostrobin, chrysin, artepillin C, and pinobanksin. The extracts exhibited high levels of total phenolic, flavonoid, and flavanone contents and moderate to high antioxidant activity. Circos plot analysis showed that specific metabolites were responsible for the high activity against
Indexed as
Anti-Bacterial AgentsAnti-Infective AgentsAntioxidantsAntiprotozoal AgentsPropolisSeasonsAnimalsBeesBrazilCandida albicansEnterococcus faecalisFlavanonesFlavonoidsLeishmaniaMicrobial Sensitivity TestsPhenolsAnti-Bacterial AgentsAnti-Infective AgentsAntioxidantsAntiprotozoal Agentsartepillin CchrysinFlavanonesFlavonoidsgalanginPhenolsPhenylpropionatespinobanksinpinocembrinpinostrobinPropolisantibacterial and antileishmanial activitiesantioxidant activitychromatographic profileflavanoneshydroxycinnamic acidsmultivariate analysispropolis raw material
Identifiers
PMID42123813
PMCPMC13165146
What Socratic holds
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