Evidence map›Paper›PMID 42124039›Full record

ArticleNutrients2026

Inhibition Mechanism, Multi-Target Regulation, and Protective Effects of Camel Casein ACE-Inhibitory Peptide on HUVECs Cells.

Fei Zhang, Hao Miao, Chenkun Huo, Ruiqi He, Yanan Qin, Jie Yang, Zhongkai Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fei ZhangCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi 830017, China.ORCID 0009-0006-5112-0303
Hao MiaoCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi 830017, China.
Chenkun HuoCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi 830017, China.
Ruiqi HeCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi 830017, China.
Yanan QinXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science & Technology, Urumqi 830017, China.
Jie YangXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science & Technology, Urumqi 830017, China.
Zhongkai ZhaoCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi 830017, China.

Funding

Key Research and Development Program of Xinjiang Uygur Autonomous Region 2023B02034-1Key Research and Development Program of Xinjiang Uygur Autonomous Region 2025B04032-001Natural Science Foundation of Xinjiang Uygur Autonomous Region 2022D01C680Xin Jiang Agriculture Research System Fund project XJARS-11
6 · The paper itself

Abstract

Hypertension is a severe global public health issue. Food-derived angiotensin-converting enzyme (ACE)-inhibitory peptides have shown great potential as safe and effective alternatives to synthetic antihypertensive drugs. Camel milk is rich in bioactive peptides. This study aimed to screen for ACE-inhibitory peptides from hydrolyzed camel casein, explore their inhibitory mechanisms and endothelial protective effects in vitro, and reveal their potential antihypertensive pathways using network pharmacology. This study screened three peptides with angiotensin-converting enzyme (ACE) inhibitory activity from enzymatically hydrolyzed camel casein components: MVPFLQPK, VPFLQPKVM, and QKWKFL, with IC

Indexed as

Angiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsCamelusCaseinsHuman Umbilical Vein Endothelial CellsPeptidesAnimalsBioactive Peptides, DietaryHumansMolecular Docking SimulationMolecular Dynamics SimulationPeptidyl-Dipeptidase AAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsBioactive Peptides, DietaryCaseinsPeptidesPeptidyl-Dipeptidase AACE-inhibitory peptidescamel caseinHUVECs cellsmolecular dockingnetwork pharmacology

Identifiers

PMID42124039
PMCPMC13165283

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.