Evidence map›Paper›PMID 42124643›Full record

ArticlebioRxiv : the preprint server for biology2026

A PLUM Job: Peptide modeLs for Understanding and engineering antiMicrobial therapeutics.

Priyanka Banerjee, Iddo Friedberg, Britta Rued, Oliver Eulenstein

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Priyanka BanerjeeDepartment of Computer Science, Iowa State University, Ames, 50011, IA, USA.
Iddo FriedbergDepartment of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, 50011, IA, USA.ORCID 0000-0002-1789-8000
Britta RuedDepartment of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, 50011, IA, USA.ORCID 0000-0003-3178-4269
Oliver EulensteinDepartment of Computer Science, Iowa State University, Ames, 50011, IA, USA.ORCID 0000-0002-5291-3798

Funding

Fine-grained Annotation of the Protein Universe through a Community of PracticeR01GM145937 · NIGMS · IOWA STATE UNIVERSITY · PI Iddo Friedberg · 2024 to 2026
$1.3M
NIGMS NIH HHS R01 GM145937
6 · The paper itself

Abstract

Motivation: Antibiotic-resistant infections in humans and animals are rising, creating an urgent need for new antimicrobial strategies. This challenge extends beyond clinical settings to food production systems; the Centers for Disease Control and Prevention estimates that foodborne pathogens cause over 48 million illnesses annually in the U.S. alone. Antimicrobial peptides (AMPs) are a promising alternative, with broad activity and lower risk of resistance. However, rational design remains challenging, especially when simultaneously controlling sequence, function, and peptide length. Results: We introduce Availability: https://github.com/priyamayur/PLUM.

Indexed as

Animal HealthAntimicrobial PeptidesDisentangled RepresentationsGenerative ModelHuman HealthVariational Autoencoders

Identifiers

PMID42124643
PMCPMC13160118

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.