Evidence map›Paper›PMID 42124713›Full record

ArticlebioRxiv : the preprint server for biology2026

Distinct Rab11-associated membrane trafficking pathways bidirectionally control neuronal extracellular vesicle cargo traffic.

Amy L Scalera, Cassandra R Blanchette, Erica C Dresselhaus, Eric Gomez, Jack Y Cheng, Avital A Rodal

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amy L ScaleraDepartment of Biology, Brandeis University, Waltham, MA.
Cassandra R BlanchetteDepartment of Biology, Brandeis University, Waltham, MA.
Erica C DresselhausDepartment of Biology, Brandeis University, Waltham, MA.
Eric GomezDepartment of Biology, Brandeis University, Waltham, MA.
Jack Y ChengDepartment of Biology, Brandeis University, Waltham, MA.
Avital A RodalDepartment of Biology, Brandeis University, Waltham, MA.ORCID 0000-0002-2051-8304

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK, THOMAS KAUFMAN · 2014 to 2026
$13.5M
NEUROSCIENCE: FROM CHANNELS TO BEHAVIORT32MH019929 · NIMH · BRANDEIS UNIVERSITY · PI GRIFFITH, LESLIE C · 1994 to 2023
$8.5M
Roles of Recycling Endosomes in Neuronal Extracellular Vesicle Cargo TrafficR01NS103967 · NINDS · BRANDEIS UNIVERSITY · PI Avital Adah Rodal · 2018 to 2026
$4.5M
Abberior 3D-STED microscope for super-resolution imagingS10OD034223 · OD · BRANDEIS UNIVERSITY · PI RODAL, AVITAL ADAH · 2023 to 2023
$1.2M
NIH HHS P40 OD018537NIH HHS S10 OD034223NIMH NIH HHS T32 MH019929NINDS NIH HHS R01 NS103967
6 · The paper itself

Abstract

Neuronal extracellular vesicles (EVs) are released from synapses, and play roles in cellular communication, proteostasis, and the spread of toxic proteins in disease. The small GTPase Rab11 is required to maintain a reservoir of EV cargoes at presynaptic terminals, but how its diverse effector proteins contribute to this function and where Rab11 acts in neurons remains unclear. Using

Identifiers

PMID42124713
PMCPMC13160047

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.