Evidence map›Paper›PMID 42125541›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Reliability of remote self-administered Web-based digital cognitive measures and comparison to in-person neuropsychological tests: Stricker Learning Span, Symbols Test, and the Mayo Test Drive Screening Battery Composite.

Morgan A Hughes, Ryan D Frank, Rita L Taylor, Winnie Z Fan, Teresa J Christianson, Walter K Kremers, John L Stricker, Mary M Machulda, Jason Hassenstab, Michelle M Mielke and 8 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Morgan A HughesDepartment of Anesthesia and Perioperative Medicine Mayo Clinic Rochester Minnesota USA.
Ryan D FrankDepartment of Quantitative Health Sciences Mayo Clinic Rochester Minnesota USA.
Rita L TaylorDepartment of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA.
Winnie Z FanDepartment of Quantitative Health Sciences Mayo Clinic Rochester Minnesota USA.
Teresa J ChristiansonDepartment of Quantitative Health Sciences Mayo Clinic Rochester Minnesota USA.
Walter K KremersDepartment of Quantitative Health Sciences Mayo Clinic Rochester Minnesota USA.
John L StrickerDepartment of Information Technology Mayo Clinic Rochester Minnesota USA.
Mary M MachuldaDepartment of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA.
Jason HassenstabDepartment of Neurology and Psychological & Brain Sciences Washington University in Saint Louis Saint Louis Missouri USA.
Michelle M MielkeDepartment of Epidemiology and Prevention Wake Forest University School of Medicine Winston-Salem North Carolina USA.
John A LucasDepartment of Psychiatry and Psychology Mayo Clinic in Florida Jacksonville Florida USA.
Paula A AduenDepartment of Psychiatry and Psychology Mayo Clinic in Florida Jacksonville Florida USA.
Gregory S DayDepartment of Neurology Mayo Clinic in Florida Jacksonville Florida USA.
Neill R Graff-RadfordDepartment of Neurology Mayo Clinic in Florida Jacksonville Florida USA.
Clifford R JackDepartment of Radiology Mayo Clinic Rochester Minnesota USA.
Jonathan Graff-RadfordDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Ronald C PetersenDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Nikki H StrickerDepartment of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA.

Funding

SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI KEJAL KANTARCI · 2019 to 2026
$33.5M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Validation of the Mayo Test Drive Screening Battery Composite and Stricker Learning Span for Early Detection and Monitoring of Cognitive Decline in Preclinical and Prodromal Alzheimer’s DiseaseR01AG081955 · NIA · MAYO CLINIC ROCHESTER · PI Nikki H Stricker · 2024 to 2026
$4.4M
Stricker Learning Span: A Computer Adaptive Word List Memory Test Optimized for Remote AssessmentR21AG073967 · NIA · MAYO CLINIC ROCHESTER · PI STRICKER, NIKKI H · 2021 to 2021
$437k
NIA NIH HHS P30 AG062677NIA NIH HHS R01 AG034676NIA NIH HHS R01 AG081955NIA NIH HHS R21 AG073967NIA NIH HHS U01 AG006786
6 · The paper itself

Abstract

introductionWe describe the reliability of remote self-administered digital cognitive measures completed via the Mayo Test Drive (MTD) web-based platform.

methodsA total of 1846 participants (mean age = 70, SD = 12, range 31-101; 48% male; 96% White; 99% non-Hispanic; 97% cognitively unimpaired) with two to four complete MTD sessions at ∼7.5-month intervals were included. Test-retest reliability was assessed using single-rating, absolute-agreement, and two-way mixed intraclass correlation coefficients (ICCs) with 95% confidence intervals. ICCs for in-person-administered traditional neuropsychological measures were compared to MTD for a subset of 244 participants. Analyses also compared reliability across demographic, residential, and session context subgroups.

resultsReliability was good for the MTD Composite (total ICC = 0.79 [0.77, 0.80]), and moderate-to-good for the primary outcome variables for each MTD subtest (total ICCs 0.70-0.83 for Stricker Learning Span and Symbols). The reliability of the remote self-administered MTD was similar to in-person-administered cognitive measures. DISCUSSION: MTD showed moderate-to-good reliability, supporting its use in longitudinal monitoring.

Indexed as

alternate form reliabilitycognitioncognitive agingcognitively unimpairedmild cognitive impairmentmobile healthneuropsychological testsneuropsychologyremote cognitive assessmentself‐administeredsmartphonetelemedicinetest–retest reliabilityunsupervised

Identifiers

PMID42125541
PMCPMC13158143

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.