ArticleEuropean journal of pediatrics2026
The ambulatory arterial stiffness index is not a measure of arterial stiffness in a selected group of children at risk of secondary hypertension.
Article in European journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The ambulatory arterial stiffness index (AASI) has emerged as an ambulatory blood pressure monitoring (ABPM) measure of stiffness and is supposedly useful in younger subjects. The objective of our study was to evaluate the relationships between the AASI and indices of arterial stiffness in a pediatric population at risk of hypertension. Cross-sectional study of children/adolescents (8-18 years) whose pulse wave velocity (PWV: carotid-to-femoral cf-PWV and heart-finger hf-PWV), augmentation index (AIx; normalized at 75 bpm: AIx
conclusionAASI is not a measure of arterial stiffness in children at risk of secondary hypertension. WHAT IS KNOWN: • The ambulatory arterial stiffness index (AASI) has emerged as an ambulatory blood pressure monitoring measure of stiffness and is supposedly useful in younger subjects. Few adult studies validated the concept of AASI as a marker of arterial stiffness, and recent studies suggested the need for AASI measurement in pediatric subjects. WHAT IS NEW: • Our cross-sectional study, which used different methods for the assessment of vascular remodeling, shows that the AASI is not a reliable marker of arterial stiffness in children at risk of secondary hypertension.
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