Evidence map›Paper›PMID 42128471›Full record

ArticleThe journal of nutrition, health & aging2026

Impacts of an app-assisted comprehensive oral frailty prevention program on oral frailty and care dependency risk in community-dwelling older adults.

Misaki Tanaka, Koichiro Matsuo, Risako Mikami, Rena Hidaka, Shunsuke Funaoka, Masayuki Kurose, Jun Aida, Akiko Kojo, Yuji Masuda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of nutrition, health & aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Misaki TanakaDepartment of Oral Health Sciences for Community Welfare, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Japan.
Koichiro MatsuoDepartment of Oral Health Sciences for Community Welfare, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Japan. Electronic address: matsuo.ohcw@tmd.ac.jp.
Risako MikamiDepartment of Advanced Biomaterials, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Japan.
Rena HidakaDepartment of Oral Health Sciences for Community Welfare, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Japan.
Shunsuke FunaokaDivision of Oral and Maxillofacial Biology, Institute for Oral Science, Matsumoto Dental University, Japan.
Masayuki KuroseDepartment of Physiology, School of Dentistry, Iwate Medical University, Japan.
Jun AidaDepartment of Dental Public Health, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Japan.
Akiko KojoFaculty of Food and Nutritional Sciences, Japan Women's University, Japan.
Yuji MasudaDivision of Oral and Maxillofacial Biology, Institute for Oral Science, Matsumoto Dental University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOral frailty (OF) is defined as a transitional stage between a healthy oral condition and functional decline. The condition is characterized by subtle impairments in oral function and may precipitate physical frailty and long term care need. As a preventive measure against OF, we have developed the Comprehensive Awareness Modification of Mouth, Chewing, and Meal Program (CAMCAM-P) integrated with a social networking service (SNS) portal app. This study examined whether the CAMCAM-P improved OF and reduced care dependency risk (CDR) among community-dwelling older adults in Japan.

designSingle-arm pre-post comparison study. SETTING AND

participantsCommunity-dwelling adults aged ≥50 years were recruited from 18 regions across Japan to participate in the CAMCAM-P.

interventionThe CAMCAM-P involved a 6-month program consisting of monthly education sessions on oral health and nutrition paired with a "CAMCAM textured lunch", supplemented by information delivery via an SNS app. Participants completed pre- and post-intervention assessments. MEASUREMENTS: Outcome measures included the Oral Frailty Index (OFI-8), Kihon Checklist (KCL), and KCL-based CDR score. Pre-post changes were evaluated using multilevel mixed-effects models with repeated observations nested within individuals, adjusting for baseline sociodemographic, behavioral, and clinical covariates. Mediation analysis using a generalized structural equation model assessed whether OF changes impacted changes in CDR.

resultsOf 651 enrolled participants, 518 (median age 72 years, 74.5% women) with complete paired data and were included. OFI-8 scores decreased significantly from 2.56 to 2.27 (p < 0.001). In adjusted multilevel models, post-intervention OFI-8 score (β = -0.29; 95% CI - 0.51 to -0.16; p < 0.001) and CDR score (β = -0.33; 95% CI -0.56 to -0.10; p = 0.006) were significantly lower than pre-intervention scores. Multilevel mediation analysis indicated that changes in OF scores accounted for 30.2% of the total effect of the intervention on the pre-post change in CDR scores (indirect effect -0.10; 95% CI -0.16 to -0.04; p = 0.002).

conclusionCAMCAM-P participation was associated with favorable improvement in OF and CDR in community-dwelling adults, with approximately one-third of this association mediated through changes in OF.

Indexed as

Frail ElderlyFrailtyMobile ApplicationsOral HealthAgedAged, 80 and overAging in PlaceFemaleGeriatric AssessmentHumansIndependent LivingJapanMaleMasticationMiddle AgedCare dependencyFrailtyNutritionOral frailtyTextured lunch

Identifiers

PMID42128471
PMCPMC13196510

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.