Evidence map›Paper›PMID 42128583›Full record

ReviewJournal of cardiac failure2026

Infiltrative and Inflammatory Cardiomyopathies: Using Imaging to Probe Mechanisms of Myocardial Dysfunction.

Chaitanya Rojulpote, Michael M Givertz, Richard N Mitchell, Robert F Padera, Raymond Y Kwong, Sanjay Divakaran, Sharmila Dorbala

Abstract readReview
In one paragraph

Review in Journal of cardiac failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chaitanya RojulpoteDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Imaging Program, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Michael M GivertzDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Richard N MitchellDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Robert F PaderaDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Raymond Y KwongDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Imaging Program, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Sanjay DivakaranDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Imaging Program, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: sdivakaran@bwh.harvard.edu.
Sharmila DorbalaDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Cardiovascular Imaging Program, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: sdorbala@bwh.harvard.edu.

Funding

Noninvasive Cardiovascular Imaging Research Training ProgramT32HL094301 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Marcelo F DI CARLI · 2010 to 2026
$7.8M
Mentoring Patient Oriented Research in Innovative Imaging and High-dimensional Data Approaches to Improve Outcomes in Cardiac AmyloidosisK24HL157648 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DORBALA, SHARMILA · 2021 to 2025
$612k
NHLBI NIH HHS K24 HL157648NHLBI NIH HHS T32 HL094301
6 · The paper itself

Abstract

Infiltrative and inflammatory cardiomyopathies comprise a spectrum of myocardial diseases defined by the accumulation of abnormal substances or inflammation within the myocardium. Although their etiologies differ, they share common mechanisms of cardiac dysfunction, such as microvascular dysfunction, denervation, impaired energetics, apoptosis, inflammation, and myocardial infiltration. While conventional cardiovascular imaging techniques assess structural and functional changes, they do not usually yield insight into underlying mechanistic processes. This review highlights the role of advanced cardiovascular imaging in identifying pathophysiologic mechanisms to improve our understanding of these disease processes in order to improve the care of patients.

Indexed as

CardiomyopathiesMyocarditisMyocardiumHumansInflammationcardiac amyloidosiscardiac sarcoidosisHeart failurehemochromatosismagnetic resonance imagingmetabolic storage diseasemicrocirculationmyocarditispositron emission tomography

Identifiers

PMID42128583
PMCPMC13178112

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.