Evidence map›Paper›PMID 42129336›Full record

ArticleBritish journal of cancer2026

Diabetes mellitus and health-related quality of life in long-term survivors of breast, colorectal or prostate cancer: a population-based prospective study.

Keyi Yang, Melissa S Y Thong, Daniela Doege, Lena Koch-Gallenkamp, Linda Weisser, Heike Bertram, Andrea Eberle, Bernd Holleczek, Alice Nennecke, Annika Waldmann and 5 more

Abstract read
In one paragraph

Article in British journal of cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Keyi YangCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Melissa S Y ThongCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. m.thong@dkfz-heidelberg.de.ORCID http://orcid.org/0000-0002-6987-705X
Daniela DoegeCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0000-0002-7499-5376
Lena Koch-GallenkampDivision of Clinical Epidemiology of Early Cancer Detection, DKFZ, Heidelberg, Germany.
Linda WeisserDivision of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany.
Heike BertramCancer Registry of North Rhine-Westphalia, Bochum, Germany.
Andrea EberleBremen Cancer Registry, Leibniz Institute for Prevention Research and Epidemiology-BIPS, Bremen, Germany.
Bernd HolleczekSaarland Cancer Registry, Saarbrücken, Germany.
Alice NenneckeHamburg Cancer Registry, Hamburg, Germany.
Annika WaldmannInstitute for Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany.
Sylke Ruth ZeissigCancer Registry of Rhineland-Palatinate, Mainz, Germany.
Ron PritzkuleitCancer Registry of Schleswig-Holstein, Lübeck, Germany.
Lina JansenDivision of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-8004-4940
Hermann BrennerDivision of Clinical Epidemiology and Aging Research, DKFZ, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6129-1572
Volker ArndtCancer Survivorship Outcomes and Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID http://orcid.org/0000-0001-9320-8684

Funding

Deutsche Krebshilfe (German Cancer Aid) 108262, 70112089, 110231
6 · The paper itself

Abstract

backgroundWe examined the association between diabetes mellitus (DM) and health-related quality of life (HRQOL) in long-term cancer survivors (LTCS) 14-24 years post-diagnosis, and evaluated the role of DM in the HRQOL of cancer survivors and cancer-free controls.

methodsWe analysed 6811 LTCS diagnosed with breast, colorectal, or prostate cancer between 1994 and 2004, surveyed in 2008-2011 and 2018-2019, and 1701 controls surveyed in 2013-2014. Multiple linear regression and linear mixed regression models were used to assess cross-sectional and prospective associations of DM and cancer with HRQOL, between participants with and without cancer, and between diabetics and non-diabetics.

resultsAt baseline, DM prevalence was 14%, and mean age of LTCS with DM was 72 years. LTCS with DM reported consistently poorer HRQOL than non-diabetic counterparts at baseline, with some HRQOL dimensions showing stronger associations with DM than with cancer in cross-sectional analysis. Although cancer generally showed a stronger association with poorer HRQOL than DM, DM was more strongly associated with worse physical functioning, global health status, pain, and appetite loss. The longitudinal perspective revealed similar associations between DM and HRQOL as the cross-sectional perspective for all scales.

conclusionThe findings highlight the need for comprehensive care strategies that address both cancer and DM to enhance health outcomes in diabetic LTCS.

Indexed as

Breast NeoplasmsCancer SurvivorsColorectal NeoplasmsDiabetes MellitusProstatic NeoplasmsQuality of LifeAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedProspective Studies

Identifiers

PMID42129336
PMCPMC13427720

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.