Evidence map›Paper›PMID 42129446›Full record

ArticleScientific reports2026

Epistemic frontiers and the distinction between causality, information, and predictability in pattern recognition.

Pablo Neirz, Héctor Allende, Carolina Saavedra

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pablo NeirzDepartamento de Informática, Universidad Técnica Federico Santa María, Valparaíso, Chile. pneirz@usm.cl.
Héctor AllendeDepartamento de Informática, Universidad Técnica Federico Santa María, Valparaíso, Chile.
Carolina SaavedraDepartamento de Informática, Universidad Técnica Federico Santa María, Valparaíso, Chile.

Funding

FONDECYT Project No. 11250727
6 · The paper itself

Abstract

High predictive accuracy is frequently misinterpreted as evidence of causal understanding or population-level signal. Models can exploit spurious correlations, confounding, or protocol-induced artefacts, while post-hoc explanations may faithfully describe model behaviour yet remain misleading about the underlying phenomenon. We propose a framework that separates three layers of evidence: (i) causal relations in the phenomenon, (ii) population-level statistical dependence, and (iii) finite-sample, protocol-dependent predictive effects. This separation clarifies why predictive success and feature attributions do not license mechanistic interpretations without additional assumptions. Under log-loss and Bayes-risk-consistent protocols, the population predictive value of adding a feature equals the conditional mutual information, providing a principled reference for "true signal". Using controlled simulations, we illustrate that bootstrap resampling can induce persistent false positives by amplifying chance correlations, and that SHAP can assign high importance to confounded variables while remaining faithful to the fitted model. These results suggest that "feature importance" is best treated as protocol-bounded evidence, and that interpretation benefits from reporting the protocol, robustness checks, and the intended inferential scope.

Indexed as

CausalityPattern Recognition, AutomatedAlgorithmsBayes TheoremComputer SimulationHumansPrediction AlgorithmsCausal machine learningConditional mutual informationConfoundingFeature attributionInterpretable machine learningRashomon effectTrustworthy AI

Identifiers

PMID42129446
PMCPMC13357541

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.