Evidence map›Paper›PMID 42129462›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Mandarin speech-based early detection of SCD: a feature-fusion residual network method.

Zhou Liu, Chao Che, Guimei He, Hanyu Wu, Lei Cai, Lili Cui, Lizhong Liang

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mandarin speech-based early detection of SCD: a feature-fusion residual network method.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhou LiuGuangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Institute of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Chao CheSchool of Software Engineering, Dalian University, Dalian, China.ORCID https://orcid.org/0000-0003-2978-5430
Guimei HeDepartment of Epidemiology and Health StatisticsSchool of Public Health, Guangdong Medical University, Zhanjiang, China.
Hanyu WuKey Laboratory of Advanced Design and Intelligent Computing (Dalian University), Ministry of Education, Dalian University, Dalian, Liaoning, China.
Lei CaiDepartment of Epidemiology and Health StatisticsSchool of Public Health, Guangdong Medical University, Zhanjiang, China.
Lili CuiGuangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Institute of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Lizhong LiangGuangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Institute of Neurology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.

Funding

2024B1515230001Affiliated Clinical Research Project of Guangdong Medical University LCYJ2021B001Basic and Applied Basic Research Foundation of Guangdong ProvinceSpecial Project for Clinical and Basic Sci&Tech Innovation of Guangdong Medical University GDMULCJC2024006Special Project of Songshan Lake Medical-Engineering Integration Innovation Centre at Guangdong Medical University 4SG22307P
6 · The paper itself

Abstract

introductionAlzheimer's disease (AD) poses a global health challenge. Early intervention during the stage of subjective cognitive decline (SCD) - a potential window for delaying disease progression - is crucial. This study aims to assess an exploratory speech-based model for rapid SCD screening.

methodThis study included 459 participants, comprising individuals with AD, mild cognitive impairment (MCI), SCD, and normal controls. We used Pic-Talk clips and Mandarin speech with residual network features for SCD screening.

resultsIn this cross-sectional study, our model achieved high performance with accuracy, recall, precision, F1, and area under the curve of 81.77 ± 2.78%, 80.53 ± 2.64%, 82.27 ± 2.38%, 81.39 ± 1.85%, and 82.85 ± 2.01%, respectively, outperforming other speech models. DISCUSSION: This non-invasive exploratory approach to SCD assessment shows potential, revealing acoustic differences at the group level between SCD and other diagnostic groups. It is expected that the future integration of biomarkers will enhance the model's accuracy and expand its applicability.

Indexed as

Alzheimer DiseaseCognitive DysfunctionSpeechAgedCross-Sectional StudiesEarly DiagnosisFemaleHumansMaleAlzheimer's disease (AD)screeningspeech recognition

Identifiers

PMID42129462
PMCPMC13171464

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.