ReviewNature cardiovascular research2026
Ischemic heart disease burden and healthcare system readiness across sub-Saharan Africa.
Review in Nature cardiovascular research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
14 authors.
Funding
Abstract
Sub-Saharan Africa is experiencing a rapid rise in ischemic heart disease, creating new challenges for regional health systems. As populations grow and urbanize, lifestyle, metabolic, nutritional and environmental factors are reshaping the burden of noncommunicable diseases. Yet health systems, historically oriented toward communicable diseases and maternal health, show variable capacity to prevent, diagnose and treat ischemic heart disease. Despite increasing recognition, systematic assessments of country-level disease burden and healthcare capacity are limited, leaving gaps for evidence-based policy. Here we address this gap by assessing healthcare system readiness across four domains: health system capacities, primary care, secondary and tertiary care, and health system context. We highlight how limitations in workforce, essential medicines, diagnostics and policy intersect with upstream drivers such as obesity, hypertension, diabetes, smoking, dietary transitions, urbanization and environmental stressors. Meeting these challenges will require coordinated investment, equitable resource allocation and integrated prevention strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.