Evidence map›Paper›PMID 42130118›Full record

ArticleCancer medicine2026

Prognostic Factors in Oropharyngeal Cancer Treated With Definitive Chemoradiotherapy.

Sheetal R Kashid, Ashwini Budrukkar, Monali Swain, Sarbani Ghosh Laskar, Vedang Murthy, Tejpal Gupta, Ajay Sasidharan, Vijay Patil, Amit Joshi, Vanita Noronha and 10 more

Abstract read
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In one paragraph

Article in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Sheetal R KashidDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Ashwini BudrukkarDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.ORCID https://orcid.org/0000-0002-6019-7859
Monali SwainDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Sarbani Ghosh LaskarDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.ORCID https://orcid.org/0000-0003-0744-4838
Vedang MurthyDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Tejpal GuptaDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Ajay SasidharanDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Vijay PatilDepartment of Medical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Amit JoshiDepartment of Medical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Vanita NoronhaDepartment of Medical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Neha MittalDepartment of Pathology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Manoj MahimkarMahimkar Lab, Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India.
Asawari PatilDepartment of Pathology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Usha PatelMahimkar Lab, Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India.
Shwetabh SinhaDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Anuj KumarDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Nandini MenonDepartment of Medical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Munita BalDepartment of Pathology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Kumar PrabhashDepartment of Medical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Jai Prakash AgarwalDepartment of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.ORCID https://orcid.org/0000-0003-0430-8558

Funding

Council of Scientific and Industrial Research, IndiaTata Memorial Centre
6 · The paper itself

Abstract

objectivesHPV-negative oropharyngeal squamous cell cancer (OPSCC) is associated with poor clinical outcomes. The main objective of this study was to evaluate prognostic factors of OPSCC treated with definitive chemoradiotherapy (CTRT). MATERIALS AND

methodsConsecutive patients of OPSCC treated with definitive CTRT in a tertiary care center from January 2013 to December 2017 were analysed retrospectively. Kaplan-Meier method was used for survival analysis, Log-rank test was used for univariate analysis (UVA), and Cox regression method was used for multivariate analysis (MVA).

resultsOut of 630 eligible patients, 543 (86.1%) had locally advanced stage according to AJCC 7

conclusionIn this predominantly HPV-negative OPSCC cohort, HPV status, T stage, RT technique, and RT doses > 66 Gy were independent prognostic factors for all outcomes.

Indexed as

ChemoradiotherapyOropharyngeal NeoplasmsAdultAgedFemaleHuman Papillomavirus VirusesHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm StagingPapillomavirus InfectionsPrognosisRadiotherapy, Intensity-ModulatedRetrospective StudiesTreatment Outcomechemoradiotherapyhead and neck oncologyhead and neck squamous cell carcinomaHPVHPV negative oropharyngeal cancerhuman papillomavirusoral canceroropharyngeal cancer

Identifiers

PMID42130118
PMCPMC13172274

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.