Evidence map›Paper›PMID 42130127›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2026

Associations of High-Sensitivity Cardiac Troponin and N-Terminal Pro-B-Type Natriuretic Peptide With Echocardiographic Features in Patients With Hypertension.

Mingdan Wang, Xihan Li, Lingyue Qiu, Zhen Wang, Jiamiao Li, Jiayi Sun, Lizhen Han, Na Yang, Yongchen Hao, Rong Hu and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mingdan WangCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Xihan LiCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Lingyue QiuCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Zhen WangCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Jiamiao LiCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Jiayi SunCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Lizhen HanCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Na YangCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Yongchen HaoCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.
Rong HuDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, Beijing, China.
Yue QiCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.ORCID 0000-0002-6709-7041
Jing LiuCenter For Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, National Clinical Research Center For Cardiovascular Diseases, Beijing, China.ORCID 0000-0002-3311-0818

Funding

Beijing Municipal Medical Research Institutes Financial Project 11000024T000002831102Beijing Municipal Medical Research Institutes Pilot Reform Project 2023-9Capital Funds for Health Improvement and Research CFH 2024-2G-1052National Key Research and Development Program of China 2022YFC3602501:2021YFC2500601National Natural Science Foundation of China 82470465
6 · The paper itself

Abstract

High-sensitivity cardiac troponin T (hs-cTnT) and/or N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels are associated with left ventricular structure and function in general populations, however, evidence regarding their relationship with multidimensional echocardiographic features in patients with hypertension remains limited. Hypertensive adults (aged ≥18 years) from a multicenter prospective cohort who underwent echocardiography from 2017 to 2020 were included in this study. Associations of serum hs-cTnT and NT-proBNP, alone and combined, with echocardiographic features were evaluated in multivariable-adjusted models. Among a total of 1803 hypertensive participants (mean age, 51.0 ± 11.9 years; 29.7% women), the median levels of hs-cTnT and NT-proBNP were 5.13 ng/L (IQR 3.68, 7.30) and 32.80 ng/L (IQR 17.85, 59.25), respectively. Participants in the highest hs-cTnT tertile showed greater left ventricular and atrial remodeling and higher flow velocity than those in the lowest tertile, including mean increases of 0.59 mm in left ventricular end-diastolic diameter (95% CI 0.02-1.16), 2.78 g/m

Indexed as

HypertensionNatriuretic Peptide, BrainPeptide FragmentsTroponin TAdultBiomarkersEchocardiographyFemaleHumansMaleMiddle AgedProspective StudiesBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Troponin T

Identifiers

PMID42130127
PMCPMC13172604

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.