Evidence map›Paper›PMID 42130752›Full record

ReviewAging medicine (Milton (N.S.W))2026

Impact of Deprescribing Among Older Adults in Primary Care Settings: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Christina Malini Christopher, Bhuvan Kc, Mark Wing Loong Cheong, Rajeev Shrestha, Sunil Shrestha, Juman Dujaili, Ali Blebil

Abstract readReview
In one paragraph

Review in Aging medicine (Milton (N.S.W)), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christina Malini ChristopherDiscipline of Clinical Pharmacy, School of Pharmaceutical Science Universiti Sains Malaysia Penang Malaysia.ORCID https://orcid.org/0000-0002-0272-2117
Bhuvan KcSchool of Clinical Sciences Queensland University of Technology Brisbane Australia.
Mark Wing Loong CheongSchool of Pharmacy Monash University Malaysia Subang Jaya Selangor Malaysia.ORCID https://orcid.org/0000-0002-8652-7369
Rajeev ShresthaNIHR Newcastle Patient Safety Research Collaboration Newcastle University Newcastle upon Tyne UK.ORCID https://orcid.org/0000-0003-1822-3969
Sunil ShresthaDepartment of Research and Academics Kathmandu Cancer Center Bhaktapur Nepal.ORCID https://orcid.org/0000-0002-9174-7120
Juman DujailiSwansea University Medical School Swansea University Singleton Park UK.
Ali BlebilSwansea University Medical School Swansea University Singleton Park UK.ORCID https://orcid.org/0000-0002-7480-1260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Deprescribing is a systematic approach aimed at reducing the number of medications that are no longer beneficial or appropriate. This study aims to assess the various types of deprescribing and the outcomes among older adults in primary health care. The electronic search for original articles was conducted using the following electronic databases: MEDLINE, EMBASE, Scopus, PsycINFO, and Global Health. The types of deprescribing interventions and their outcomes in older adults were assessed and compared with those of non-intervention. The risk of bias was assessed using the Robins tool. Eighteen randomized controlled trials were included after full-text screening. These studies evaluated a range of deprescribing interventions implemented in primary healthcare settings. The interventions included medication reviews, academic detailing, pharmacist-led deprescribing, computerized decision-support tools, structured education, patient-centered communication, and coordinated medication risk management. Quantitative analysis revealed that two studies reported a statistically significant reduction in patient falls due to deprescribing (OR: 0.67; 95% CI: [0.46, 0.98]; I Trial Registration: Prospero CRD42023464445.

Indexed as

deprescribingmedication reviewolder adultsoutcomessystematic review

Identifiers

PMID42130752
PMCPMC13163933

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.