ReviewJAC-antimicrobial resistance2026
The effectiveness of intravenous (IV) to oral (PO) antibiotic switch (IVOS) interventions in managing community- and hospital-acquired pneumonia-a systematic review.
Review in JAC-antimicrobial resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Prolonged intravenous (IV) antibiotic therapy in hospitalized patients with pneumonia increases healthcare costs and hospital length of stay compared to oral (PO) therapy. Antimicrobial stewardship (AMS) interventions promoting timely IV-to-PO antibiotic conversion may reduce healthcare burden without compromising patient outcomes. Optimal design and implementation of such interventions in different healthcare settings, including respiratory medicine remain unclear. Objectives: The aim of this study was to evaluate the effectiveness of interventions designed to improve IV-to-PO antibiotic switching practices in managing community-acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP). Methods: The review was registered with PROSPERO (CRD420251039180). PubMed, Scopus, Web of Science, The Cochrane Library databases were searched for studies published from 1995 to 2024 focusing on CAP and/or HAP management or antimicrobials indicated for respiratory infections. Two reviewers independently screened studies using Results: 58 studies were included. Interventions included clinical guideline/protocol implementation ( Conclusion: Existing AMS interventions effectively promote IV-to-PO switching in CAP/HAP management. Healthcare systems should consider more than one intervention to optimize IV-to-PO antibiotic switch.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.