SynthesisFrontiers in public health2026
The effect of dietary nitrate on weight management: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Obesity has emerged as a significant global public health concern. Despite its potential therapeutic benefits, the existing evidence regarding dietary nitrate supplementation remains inconclusive. This systematic review and meta-analysis aimed to evaluate the effects of dietary nitrate intake on obesity-related outcomes. Methods: A comprehensive search of randomized controlled trials (RCTs) investigating nitrate supplementation in adults with obesity was conducted across PubMed, Scopus, Web of Science, and Embase up to April 2026. The primary outcomes included body weight, body mass index (BMI), blood pressure, and lipid-related markers. The study adhered to the PRISMA 2020 guidelines for reporting. Results: Eight RCTs involving 199 participants were included in the meta-analysis. No significant effects of nitrate supplementation were observed on body weight, BMI, or diastolic blood pressure (DBP). A statistically significant reduction was observed in systolic blood pressure (SBP, 95% CI: -0.63 to -0.01; SMD = -0.32, Conclusion: Dietary nitrate supplementation exerts favorable effects on lipid parameters and systolic blood pressure, with no remarkable impacts on body weight and BMI observed. Given the relatively small sample size of the included evidence, future large-sample, high-quality, long-term randomized controlled trials are essential to confirm and reinforce the present results. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, CRD420251078542.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.