ArticleFrontiers in stroke2026
Real-world characteristics and outcomes of ischemic stroke: a Peruvian multicenter analysis from the RES-Q registry.
Article in Frontiers in stroke, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ischemic stroke in Peru: a scoping review of trends, outcomes, and evidence gaps.Frontiers in epidemiology · 2026Pooled it
- The Quindío stroke network: impact of an integrated care model on mortality and functional outcomes in a middle-income country.Frontiers in stroke · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To characterize and compare clinical profiles, care times, and functional outcomes between thrombolyzed and non-thrombolyzed patients with acute ischemic stroke (IS) within the Peruvian healthcare system using real-world data from the RES-Q registry. Methods: A retrospective multicenter cohort study was conducted. Data from adult patients with acute IS registered between January 2023 and June 2025 across five hospital centers in Peru (Lima, Arequipa, Cusco) were analyzed. The primary exposure was intravenous thrombolysis (IVT). Primary outcomes were functional independence [modified Rankin Scale (mRS) 0-2] at discharge, symptomatic intracranial hemorrhage (sICH), and in-hospital mortality. Multivariable logistic regression was used to identify independent predictors of poor functional outcome and mortality. Results: Of 1,780 patients with IS, 252 (14.2%) received IVT. Despite presenting with more severe strokes (higher median NIHSS, Conclusion: This real-world multicenter study in Peru demonstrates that IVT is feasible and effective, associating with significantly better functional outcomes despite treatment of a more severely affected cohort. The study validates the safety profile of IVT in this setting and identifies critical areas for quality improvement, particularly in reducing door-to-needle times and addressing disparities in access to mechanical thrombectomy. Our findings support the expansion and optimization of acute stroke reperfusion protocols in Peru and similar resource-limited healthcare systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.