PCSK9 inhibitors × lipids

TrialJournal of the American Heart Association2026

Low-Density Lipoprotein Cholesterol Lowering With Inclisiran Plus Usual Care in Recent Acute Coronary Syndrome: VICTORION-INCEPTION, a Randomized, Controlled, Open-Label Trial.

Kirk U Knowlton et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 400 people · 2026

Randomised comparison

Probably raised lipids

27×14× to 50×

Bigger than almost all on the map

As reported

OR 26.58, 95% CI 14.1–50.0

One number in the abstract

the abstract, start to end

<55 mg/dL: 63.2% versus 8.5%, OR, 26.58 [95% CI, 14.14-49.98];

← favours treatmentfavours comparator →
could be chance
Lipids
OR 26.5814.1–50.0
PCSK9 inhibitorsLipids

PCSK9 inhibitors × lipidshelps?settled

unlikelylikely
0.930.93 without it
← favours comparatorfavours treatment →
this papermore certainless certain
1 / 5

Not cited yet

The trial

Full record →Abstract, authors, funding and every citing paper · PMID 42132192